MEtatastic Renal Carcinoma LINes

NCT ID: NCT03928964

Last Updated: 2019-04-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

440 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-15

Study Completion Date

2019-04-30

Brief Summary

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The hypothesis of this study are as follows:

* Prognostic evaluation of patients based on an integrative model provides better assessment of overall survival, and thus improves setting of care goals.
* In a routine care population, antitumour drugs may have a significant impact on overall survival through their targeted antitumor effect, but also through their toxicity profile and their impact on comorbidities.
* The optimization of patient support (supportive care, drug tolerance monitoring) can have an impact on the prognosis.

Detailed Description

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Conditions

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Renal Cell Carcinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. Patients with locally advanced or metastatic renal cell carcinoma
2. Whose first-line treatment included at least one anti-angiogenic agent (tyrosine kinase inhibitor or monoclonal antibodies) and / or an mTOR inhibitor;
3. Whatever was the overall ECOG-PS score (Eastern Cooperative Oncology Group Performance Status) at treatment initiation time
4. With first-line treatment carried out between 2007 and June 2016.

Exclusion Criteria

1. Patient previously treated with only one cytokine (Interferon α2a, high-dose interleukin-2)
2. Refusal of processing of personal data
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Besancon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Benoit Rousseau, MD

Role: PRINCIPAL_INVESTIGATOR

Henri Mondor University Hospital

Locations

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CHU de Besançon

Besançon, , France

Site Status

Hôpital Henri Mondor

Créteil, , France

Site Status

Hôpital Nord Franche-Comté Montbéliard

Montbéliard, , France

Site Status

Hôpital Cochin

Paris, , France

Site Status

Hôpital Européen Georges Pompidou

Paris, , France

Site Status

Hôpital Saint-Louis

Paris, , France

Site Status

Institut Mutualiste Montsouris

Paris, , France

Site Status

Hôpital d'Instruction des Armées de Bégin

Saint-Mandé, , France

Site Status

Countries

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France

Other Identifiers

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P/2017/342

Identifier Type: -

Identifier Source: org_study_id