Trial Outcomes & Findings for Study Comparing the P200TE and the P200TxE in Glaucoma Patients (NCT NCT03912584)

NCT ID: NCT03912584

Last Updated: 2022-09-23

Results Overview

Scores will be based on a 4 point grading scale (0 to 3), with 0 corresponding to failure, 1 is poor, 2 is fair, and 3 is good. The four point scale is defined as follows: 0 indicates the scan is a failure, and contains no clinically useful information. No relevant structures are visible in the scan. 1. indicates the condition of the structure or feature being assessed is poor, and it contains very limited clinical utility. 2. indicates the condition of the structure or feature being assessed is fair or average. It contains some useful clinical information and therefore provides adequate clinical utility. 3. indicates the condition of the structure or feature being assessed is good. It contains useful clinical information. The clinical utility is high or good.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

10 participants

Primary outcome timeframe

1 day (start: April 29, 2019 - completed: April 30, 2019)

Results posted on

2022-09-23

Participant Flow

Participant milestones

Participant milestones
Measure
Optical Coherence Tomographer
P200TE: The P200TE Ophthalmoscope provides widefield Scanning Laser Ophthalmoscope (SLO) fundus imaging and Optical Coherence Tomography (OCT) imaging in one device. P200TxE: The P200TxE Ophthalmoscope provides widefield Scanning Laser Ophthalmoscope (SLO) fundus imaging and Optical Coherence Tomography (OCT) imaging in one device.
Overall Study
STARTED
10
Overall Study
COMPLETED
10
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Optical Coherence Tomographer
n=10 Participants
P200TE: The P200TE Ophthalmoscope provides widefield Scanning Laser Ophthalmoscope (SLO) fundus imaging and Optical Coherence Tomography (OCT) imaging in one device. P200TxE: The P200TxE Ophthalmoscope provides widefield Scanning Laser Ophthalmoscope (SLO) fundus imaging and Optical Coherence Tomography (OCT) imaging in one device.
Age, Categorical
<=18 years
0 Participants
n=10 Participants
Age, Categorical
Between 18 and 65 years
5 Participants
n=10 Participants
Age, Categorical
>=65 years
5 Participants
n=10 Participants
Sex/Gender, Customized
Male or Female
10 Participants
n=10 Participants
Region of Enrollment
United States
10 participants
n=10 Participants
Glaucoma in Subject eye
10 Participants
n=10 Participants

PRIMARY outcome

Timeframe: 1 day (start: April 29, 2019 - completed: April 30, 2019)

Population: The average score (0-3) for clinical utility and clinical quality for the P200TxE does not apply to P200TE scans, and the average score (0-3) for clinical utility and clinical quality for the P200TE does not apply to P200TxE scans. 10 subjects were imaged in total, however clinical utility and quality were measured separately for the three outcomes described below (1. Indy posterior scans, 2. Indy peripheral scans, 3. Monaco scans).

Scores will be based on a 4 point grading scale (0 to 3), with 0 corresponding to failure, 1 is poor, 2 is fair, and 3 is good. The four point scale is defined as follows: 0 indicates the scan is a failure, and contains no clinically useful information. No relevant structures are visible in the scan. 1. indicates the condition of the structure or feature being assessed is poor, and it contains very limited clinical utility. 2. indicates the condition of the structure or feature being assessed is fair or average. It contains some useful clinical information and therefore provides adequate clinical utility. 3. indicates the condition of the structure or feature being assessed is good. It contains useful clinical information. The clinical utility is high or good.

Outcome measures

Outcome measures
Measure
Optical Coherence Tomographer - P200TE
n=10 Participants
P200TE: The P200TE Ophthalmoscope provides widefield Scanning Laser Ophthalmoscope (SLO) fundus imaging and Optical Coherence Tomography (OCT) imaging in one device.
Optical Coherence Tomographer - P200TxE
n=10 Participants
P200TxE: The P200TxE Ophthalmoscope provides widefield Scanning Laser Ophthalmoscope (SLO) fundus imaging and Optical Coherence Tomography (OCT) imaging in one device.
Qualitative B-Scan Assessment
Average score (0-3) for clinical utility and clinical quality Indy (P200TxE) Posterior scans
2.78 Mean score on a scale (0-3)
Standard Deviation .45
Qualitative B-Scan Assessment
Average score (0-3) for clinical utility and clinical quality Indy (P200TxE) Peripheral scans
2.77 Mean score on a scale (0-3)
Standard Deviation .46
Qualitative B-Scan Assessment
Average score (0-3) for clinical utility and clinical quality Monaco (P200TE) scans
2.08 Mean score on a scale (0-3)
Standard Deviation .64

SECONDARY outcome

Timeframe: 1 day

Analysis of safety will be assessed through adverse events reported by the site and documented on each subject's case report form. No AEs were recorded during this study.

Outcome measures

Outcome measures
Measure
Optical Coherence Tomographer - P200TE
n=10 Participants
P200TE: The P200TE Ophthalmoscope provides widefield Scanning Laser Ophthalmoscope (SLO) fundus imaging and Optical Coherence Tomography (OCT) imaging in one device.
Optical Coherence Tomographer - P200TxE
n=10 Participants
P200TxE: The P200TxE Ophthalmoscope provides widefield Scanning Laser Ophthalmoscope (SLO) fundus imaging and Optical Coherence Tomography (OCT) imaging in one device.
Number of Participants With Adverse Events
0 Participants
0 Participants

Adverse Events

Optical Coherence Tomographer: P200TE

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Optical Coherence Tomographer: P200TxE

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Michael Sinai, PhD

Optos

Phone: +1 800 854 3039

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place

Restriction type: LTE60