NUTRI-HAB - Posttreatment Rehabilitation of Nutrition Impact Symptoms in Head and Neck Cancer Survivors

NCT ID: NCT03909256

Last Updated: 2019-12-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

71 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-04-15

Study Completion Date

2019-12-09

Brief Summary

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The study is a randomised controlled trial that aims to test the effect of a residential rehabilitation program with a focus on eating problems after treatment in head and neck cancer survivors. The study will furthermore investigate whether selected nutrition screening and assessment tools can be used to identify head and neck cancer survivor who benefit from the program.

Detailed Description

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This study is a randomised controlled trial with following objectives:

1. To test the effect of a targeted residential rehabilitation program with focus on the physical, psychological and social aspects of eating problems on body weight, health-related quality of life and physical function in curatively treated head and neck cancer survivors 1-5 years after completion of radiation therapy
2. To test whether a potential effect of the program is associated with/dependent of the participants' score in Scores Patient-Generated Subjective Global Assessment Short Form (PG-SGA-SF), Nutrition Risk Screening 2002 (NRS 2002) or M.D. Anderson Dysphagia Inventory (MDADI) at baseline

Conditions

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Head and Neck Cancer

Keywords

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Rehabilitation Nutrition impact symptoms Quality of life

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Investigators
The investigator will be blinded when performing the data analyses. Hence, data will be anonymised before analysis and the investigator will not know whether the group of subjects were allocated to the control or the intervention group.

Results from blinded data analyses will be interpreted by project group before unblinding.

Study Groups

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NUTRI-HAB

The intervention group participates in a targeted rehabilitation program 'NUTRI-HAB' with a focus on eating problem after treatment for head and neck cancer. The program comprises:

* a five day residential stay with patient education
* a two day follow-up residential stay after 3 months
* two telephone consultations with clinical dietitian between the two residential stays.

Group Type EXPERIMENTAL

NUTRI-HAB

Intervention Type OTHER

The rehabilitation program is a coordinated multidisciplinary effort involving several specialists e.g. clinical dietitians, nurses, physiotherapists, occupational therapists (responsible for dysphagia management in Denmark), psychologists and social workers.

The program includes group sessions with patient education on how to handle the different aspects of living with eating problems and other late effects. Practical kitchen exercises, physical activity sessions and instruction in swallowing training are included. Individual counseling sessions with clinical dietitians and other health professionals (e.g. physicians) are offered depending on participants' needs.

Participants stay at the premises and all meals throughout the day are served in the dining room or in the café. Foods of different textures and flavors are served to inspire participants and to allow them to experiment.

Between the initial stay and follow-up participants are contacted twice by a clinical dietitian.

Control group

The control group receives no intervention other than usual care in the study period.

After 3 months, the control group will be offered participation in the same residential rehabilitation program as the intervention group parcitipated in.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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NUTRI-HAB

The rehabilitation program is a coordinated multidisciplinary effort involving several specialists e.g. clinical dietitians, nurses, physiotherapists, occupational therapists (responsible for dysphagia management in Denmark), psychologists and social workers.

The program includes group sessions with patient education on how to handle the different aspects of living with eating problems and other late effects. Practical kitchen exercises, physical activity sessions and instruction in swallowing training are included. Individual counseling sessions with clinical dietitians and other health professionals (e.g. physicians) are offered depending on participants' needs.

Participants stay at the premises and all meals throughout the day are served in the dining room or in the café. Foods of different textures and flavors are served to inspire participants and to allow them to experiment.

Between the initial stay and follow-up participants are contacted twice by a clinical dietitian.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Cancer of the larynx, pharynx or oral cavity
* Treatment with radiation therapy completed 1-5 years before inclusion
* Curatively treated
* Expression of interest in participating in the rehabilitation program in a preceding survey
* Self-reliant and no need for assistance with personal hygiene etc.

Exclusion Criteria

* Active cancer disease at the time of recruitment
* Not being able to speak and understand Danish
* No permanent residence in Denmark
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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REHPA, The Danish Knowledge Centre for Rehabilitation and Palliative Care

OTHER

Sponsor Role collaborator

University of Southern Denmark

OTHER

Sponsor Role collaborator

University College Copenhagen

OTHER

Sponsor Role collaborator

Odense Patient Data Explorative Network

OTHER

Sponsor Role collaborator

Rigshospitalet, Denmark

OTHER

Sponsor Role collaborator

Odense University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Marianne Boll Kristensen

PhD student, Clinical dietitian

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ann-Dorthe Zwisler, Professor

Role: STUDY_DIRECTOR

REHPA, The Danish Knowledge Centre for Rehabilitation and Palliative Care

Locations

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REHPA, The Danish Knowledge Centre for Rehabilitation and Palliative Care

Nyborg, , Denmark

Site Status

Countries

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Denmark

References

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Kristensen MB, Wessel I, Beck AM, Dieperink KB, Mikkelsen TB, Moller JK, Zwisler AD. Rationale and design of a randomised controlled trial investigating the effect of multidisciplinary nutritional rehabilitation for patients treated for head and neck cancer (the NUTRI-HAB trial). Nutr J. 2020 Mar 17;19(1):21. doi: 10.1186/s12937-020-00539-7.

Reference Type DERIVED
PMID: 32183835 (View on PubMed)

Other Identifiers

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18/14847

Identifier Type: -

Identifier Source: org_study_id