ToothWave Plaque and Gingivitis Study

NCT ID: NCT03885323

Last Updated: 2020-11-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

86 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-02-28

Study Completion Date

2019-04-15

Brief Summary

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The objective of the study is to evaluate the safety and efficacy of the home-use device Silk'n toothbrush (ToothWave) for the improvement in dental health through the reduction of plaque, gingivitis, and calculus.

Detailed Description

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This is a single blind, prospective study aimed to evaluate the safety and efficacy of the Silk'n toothbrush in reduction of gingivitis, dental plaque and calculus.

The study includes 84 treatment sessions, twice a day, and 4 clinic visits over a period of 6 weeks.

One treatment group (Silk'n toothbrush - ToothWave) and 1 control group (an ADA approved power toothbrush (PTB)) will participate in the study.

For each patient, assessment data will be collected at baseline, 4 weeks, and at 6 weeks. The average data sets will be calculated for each group.

Treatment is defined as a timed 2 minutes of teeth brushing in a regular man-ner, twice a day (morning and evening). Brushing will be undertaken using the Silk'n toothbrush and standard fluoride toothpaste. The control group will use a regular PTB and standard fluoride toothpaste.

Conditions

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Gingivitis Plaque Calculus, Dental

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Single blind prospective study
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors
Participants will not know if the toothbrush is a treatment or control brush. Outcome assessor will be blinded as well and will not know which product was dispensed to which participant.

Study Groups

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Treatment group

The treatment is conducted with the ToothWave toothbrush Intervention: brushing with RF-utilizing powered toothbrush

Group Type EXPERIMENTAL

RF utilizing powered toothbrush

Intervention Type DEVICE

RF utilizing Powered toothbrush

Control group

Regular powered toothbrush Intervention: brushing with a regular powered toothbrush with no RF

Group Type PLACEBO_COMPARATOR

Control placebo with no RF

Intervention Type DEVICE

Placebo control, with no RF

Interventions

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RF utilizing powered toothbrush

RF utilizing Powered toothbrush

Intervention Type DEVICE

Control placebo with no RF

Placebo control, with no RF

Intervention Type DEVICE

Other Intervention Names

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RF toothbrush

Eligibility Criteria

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Inclusion Criteria

1. Adult subjects aged 18-70, that are in good health.
2. Subject must have:

2.2. Baseline gingivitis (MGI) score of at least 1.80, 2.3. Dental Plaque mean score greater than 0.6 according to the RMNPI Index. 2.4. Total Calculus deposits greater than 7 according to the Volpe-Manhold Index.
3. Have a minimum of 20 'scorable' teeth (excluding 3rd molars).
4. The subjects should understand the information provided about the investigative nature of the treatment, possible benefits and side effects. Subjects will sign the Informed Consent Form.
5. The subjects should be willing to comply with the study procedure and schedule, including the follow up visits.

Exclusion Criteria

1. Current or history of oral cavity cancer or oropharyngeal cancer.
2. Pacemaker or internal defibrillator, or any other active electrical implant anywhere in the body.
3. Pregnant or nursing by subject report.
4. Any active condition in the oral cavity at the discretion of the investigator.
5. Any surgery in the oral cavity within 3 months prior to treatment, or before complete healing.
6. Subjects that do not brush regularly.
7. Any condition that might make it unsafe for the subject to participate in this study, at the discretion of the investigator.
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Home Skinovations Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jeffry L. Milleman, DDS, MPA

Role: PRINCIPAL_INVESTIGATOR

Salus Research

Locations

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Salus research

Fort Wayne, Indiana, United States

Site Status

Countries

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United States

Other Identifiers

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DO116217A

Identifier Type: -

Identifier Source: org_study_id