Assessment of the Influence of Cleft Repair on Microcirculation of the Palate

NCT ID: NCT03877666

Last Updated: 2025-07-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-08-04

Study Completion Date

2025-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Investigators aim to evaluate the influence of cleft surgery on the tissue microcirculation of the palate with a non-invasive measurement.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cleft Palate Cleft Lip and Palate

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* patients with orofacial clefts, who undergo routine cleft repair

Exclusion Criteria

* missing datasets
* no signed consent for research.
Minimum Eligible Age

6 Months

Maximum Eligible Age

13 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University Hospital, Basel, Switzerland

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Benito K Benitez, MD DDS MHBA

Role: PRINCIPAL_INVESTIGATOR

University Basel and University Hospital Basel

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Universitätsspital Basel

Basel, , Switzerland

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Switzerland

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Benito K Benitez, MD DDS MHBA

Role: CONTACT

615565285 ext. 0041

Andreas A Mueller, MD DDS PhD

Role: CONTACT

613286095 ext. 0041

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Benito K Benitez, MD, DDS

Role: primary

615565285 ext. 0041

Andreas A Mueller, MD, DDS, PhD

Role: backup

13286095 ext. 0041

References

Explore related publications, articles, or registry entries linked to this study.

Huang MH, Lee ST, Rajendran K. Clinical implications of the velopharyngeal blood supply: a fresh cadaveric study. Plast Reconstr Surg. 1998 Sep;102(3):655-67. doi: 10.1097/00006534-199809030-00007.

Reference Type BACKGROUND
PMID: 9727428 (View on PubMed)

Mueller AA, Schumann D, Reddy RR, Schwenzer-Zimmerer K, Mueller-Gerbl M, Zeilhofer HF, Sailer HF, Reddy SG. Intraoperative vascular anatomy, arterial blood flow velocity, and microcirculation in unilateral and bilateral cleft lip repair. Plast Reconstr Surg. 2012 Nov;130(5):1120-1130. doi: 10.1097/PRS.0b013e318267d4fb.

Reference Type BACKGROUND
PMID: 23096613 (View on PubMed)

Woo AS. Evidence-Based Medicine: Cleft Palate. Plast Reconstr Surg. 2017 Jan;139(1):191e-203e. doi: 10.1097/PRS.0000000000002854.

Reference Type BACKGROUND
PMID: 28027255 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

Microcirculation Palate

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.