The INFORM Study: Rotational Fractional Resection for Submental Contouring

NCT ID: NCT03853980

Last Updated: 2020-03-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

21 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-03-18

Study Completion Date

2020-10-31

Brief Summary

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Efficacy and safety of Rotational Fractional Resection (skin resection) in patients with moderate to severe submental skin laxity.

Detailed Description

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This is a prospective, multi-center, single-arm (non-randomized), interventional cohort, non-significant risk (NSR) study designed to investigate the efficacy and safety of Rotational Fractional Resection (skin resection) in patients with moderate to severe submental skin laxity. The total duration of study participation for each subject is approximately up to 4 months for each subject from the screening visit to the exit visit. The follow-up period will be approximately 3 months after the procedure. Eligible subjects will complete a total of 11 study visits: screening, procedure, and follow-up visits at 1, 2-4, 7, 14, 21, 30, 45, 60, and 90 days post-procedure.

Conditions

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Skin Laxity

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Rotational fractional resection (RFR)

Single treatment of skin resection (removal of loose skin)

Group Type EXPERIMENTAL

Focal Contouring System

Intervention Type DEVICE

Single treatment of skin resection (removal of loose skin)

Interventions

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Focal Contouring System

Single treatment of skin resection (removal of loose skin)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Healthy male or female
* At least 30 years old
* Moderate to severe submental laxity
* Agree to maintain weight (±5%) for the duration of the study

Exclusion Criteria

* Greater than mild submental fat
* Previous intervention to treat submental fat or skin laxity
* Use of aspirin, ibuprofen, naproxen, or Vitamin E within 14 days of the procedure
* Severe acne, cystic acne or acne scars on neck
* Trauma of chin or neck area
* Skin infection or rash on neck
* Psoriasis, hyperpigmentation, eczema, rosacea or vitiligo
* History of scarring
* Body mass index (BMI) \>30
* Clinically significant bleeding disorder
* Anemia, kidney disease, or liver disease
Minimum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Recros Medica, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Robin McIntosh

Role: STUDY_DIRECTOR

Recros Medica

Locations

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Aesthetx

Campbell, California, United States

Site Status

Clinical Testing of Beverly Hills

Encino, California, United States

Site Status

Westside Aesthetics

Los Angeles, California, United States

Site Status

ATS Clinical Research

Santa Monica, California, United States

Site Status

Moradi MD

Vista, California, United States

Site Status

AboutSkin Research

Greenwood Village, Colorado, United States

Site Status

Washington Institute of Dermatologic Laser Surgery

Washington D.C., District of Columbia, United States

Site Status

DeNova Research

Chicago, Illinois, United States

Site Status

Juva Skin and Laser Center

New York, New York, United States

Site Status

Clinical Research Center of the Carolinas

Charleston, South Carolina, United States

Site Status

Brian Biesman, MD

Nashville, Tennessee, United States

Site Status

Bellaire Dermatology Associates

Bellaire, Texas, United States

Site Status

Sundaram Dermatology, Cosmetic & Laser Surgery Center

Fairfax, Virginia, United States

Site Status

Premier Clinical Research

Spokane, Washington, United States

Site Status

Countries

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United States

Other Identifiers

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CLP-0006

Identifier Type: -

Identifier Source: org_study_id

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