Retrospective Epidemiological Study of Locally Advanced Non Small Cell Lung Cancer Patients in Brazil

NCT ID: NCT03836469

Last Updated: 2024-02-20

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 403 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2019-09-25
• Study Completion Date: 2022-06-09

Brief Summary

RELANCE is a large multi-institutional study that aims to retrospectively collect information about diagnostic, treatment and outcome of patients diagnosed with locally advanced NSCLC in Brazil. It is hypothesized that there is a great heterogeneity in treatment patterns owing to inequities in access to adequate staging methods, optimal treatment and multidisciplinary teams in Brazil.

Detailed Description

RELANCE study will collect sociodemographic and clinical data of patients diagnosed with locally advanced NSCLC in the period of January 2015 and Jun 2019 in the participating institutions. Socio-demographic characteristics, clinicopathological features, treatments patterns and outcomes will be recovered from medical charts. Disease status and survival data will be collected up to the last date of follow-up June 2021.

Conditions

Lung Cancer, Non-small Cell

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Eligibility Criteria

Inclusion Criteria

1. Patients aged 18 years or older;

2. Histologically or cytological diagnosis of NSCLC in the period of January 2015 to December 2016;

3. Locally Advanced NSCLC defined as clinical stage IIIA and IIIB according to 7th Edition TNM Staging System;

4. Any NSCLC histological subtype and molecular mutation;

5. Any Eastern Cooperative Oncology Group (ECOG) Performance Status (0 to 4) at diagnosis;

6. Patients assigned by treating physician to any therapy or palliative care;

7. Access to patient medical chart for data collection.

Exclusion Criteria

1. Small cell lung cancer and non-invasive NSCLC;

2. Synchronic NSCLC or second primary tumour in the last 5 years (except non-melanoma skin cancer).

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

AstraZeneca

INDUSTRY

Sponsor Role: collaborator

Latin American Cooperative Oncology Group

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Vladmir Cláudio Cordeiro de Lima

Role: PRINCIPAL_INVESTIGATOR

Latin American Cooperative Oncology Group

Locations

AC Camargo

São Paulo, São Paulo, Brazil

Countries

Brazil

Other Identifiers

LACOG 0118

Identifier Type: -

Identifier Source: org_study_id