Systolic Time Intervals a Prognostic Tool of Heart Failure in Emergency Departement (STI/AHF)

NCT ID: NCT03831204

Last Updated: 2020-07-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

642 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-02-20

Study Completion Date

2019-06-30

Brief Summary

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The performance of STIs and clinical scores alone and their combination to predict short term prognosis of acute decompensated heart failure.

Detailed Description

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Acute heart failure is a leading cause of hospitalization and death.Prediction of these adverse events is still challenging.

STI is an old technique based on the recording of two parameters: electrocardiogram and phonocardiogram, and from them measuring the different systolic intervals:

pre-ejection period (PEP),electro-mechanic activation time (EMAT), Left ventricular ejection time (LVET) and systolic time ratio (RTS) were measured.

The aim of these study is to demonstrate whether systolic time intervals (STIs) can improve clinical scores EFFECT (Enhanced Feedback for Effective Cardiac Treatment) and GWTG-HF (Get With the Guidelines-Heart Failure) for predicting 30 day mortality and readmission in patients with acute decompensated heart failure (ADHF) in the ED.

Conditions

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Dyspnea Heart Failure

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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AHF/HFpEF

AHF with preserved ejection fraction Acoustic cardiography was performed for all participants using the BIOPAC Prognostic scores were calculated for every patient

biopac

Intervention Type DEVICE

Acoustic cardiography was performed for all participants using the BIOPAC system with "Student Lab" software version 3.7.2. An electrocardiogram was obtained by two electrodes placed at the right upper limb and the lower left limb. Simultaneously heart sounds were recorded with a specific sensor placed at the mitral focus.

prognostic scores

Intervention Type DIAGNOSTIC_TEST

Effect and GWTGHF were calculated for every patient

AHF/HFrEF

AHF with reduced ejection fraction Acoustic cardiography was performed for all participants using the BIOPAC Prognostic scores were calculated for every patient

biopac

Intervention Type DEVICE

Acoustic cardiography was performed for all participants using the BIOPAC system with "Student Lab" software version 3.7.2. An electrocardiogram was obtained by two electrodes placed at the right upper limb and the lower left limb. Simultaneously heart sounds were recorded with a specific sensor placed at the mitral focus.

prognostic scores

Intervention Type DIAGNOSTIC_TEST

Effect and GWTGHF were calculated for every patient

Interventions

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biopac

Acoustic cardiography was performed for all participants using the BIOPAC system with "Student Lab" software version 3.7.2. An electrocardiogram was obtained by two electrodes placed at the right upper limb and the lower left limb. Simultaneously heart sounds were recorded with a specific sensor placed at the mitral focus.

Intervention Type DEVICE

prognostic scores

Effect and GWTGHF were calculated for every patient

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* non traumatic dyspnea
* age more than 18 years old.

Exclusion Criteria

* ECG diagnostic for acute myocardial infarction
* ischemic chest pain within the prior 24 hours
* history of a heart transplant
* pericardial effusion
* chest wall deformity suspected of causing dyspnea
* coma
* shock,Mechanical Ventilation, vasopressor drugs
* arrhythmia serious and sustained,
* pace maker
* severe mitral valve disease,
* severe pulmonary arterial hypertension
* renal failure with creatinine \>350micromol/l
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Monastir

OTHER

Sponsor Role lead

Responsible Party

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Pr. Semir Nouira

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nouira Semir, Pr

Role: PRINCIPAL_INVESTIGATOR

University hospital of Monastir

Locations

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Emergency department of university hospital Fattouma Bourguiba of Monastir Monastir, Monastir Tunisia

Monastir, , Tunisia

Site Status

Countries

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Tunisia

Related Links

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http://www.urgencemonastir.com

official department website

Other Identifiers

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STI in AHF prognostic

Identifier Type: -

Identifier Source: org_study_id

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