Transpacific TAVR Registry

NCT ID: NCT03826264

Last Updated: 2026-01-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

10000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-06-15

Study Completion Date

2036-12-31

Brief Summary

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This registry evaluates the long-term outcome of Transcatheter aortic valve replacement (TAVR) in real-world clinical practice.

Detailed Description

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This study is connected with Asian TAVR registry(NCT02308150). Some subjects from Asian TAVR registry continue 10 years follow-up on this TP-TAVR registry.

Conditions

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Heart Valve Diseases Aortic Valve Insufficiency

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Korea Centers

Seoul, Korea All Patients undergoing TAVR

TAVR

Intervention Type PROCEDURE

transcatheter aortic valve replacement (TAVR)

Stanford University

California, USA All Patients undergoing TAVR

TAVR

Intervention Type PROCEDURE

transcatheter aortic valve replacement (TAVR)

Northwestern University

Evanston, Illinois, USA All Patients undergoing TAVR

TAVR

Intervention Type PROCEDURE

transcatheter aortic valve replacement (TAVR)

Cheng-Hsin Hospital

Taipei, Taiwan All Patients undergoing TAVR

TAVR

Intervention Type PROCEDURE

transcatheter aortic valve replacement (TAVR)

Interventions

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TAVR

transcatheter aortic valve replacement (TAVR)

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All patients undergoing TAVR
* Informed consent
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Duk-Woo Park, MD

OTHER

Sponsor Role lead

CardioVascular Research Foundation, Korea

OTHER

Sponsor Role collaborator

Responsible Party

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Duk-Woo Park, MD

Professor, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Alan Ching Yuen Yeung, MD

Role: PRINCIPAL_INVESTIGATOR

Stanford University

James D. Flaherty, MD

Role: PRINCIPAL_INVESTIGATOR

Northwestern University

Locations

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Stanford University

Stanford, California, United States

Site Status RECRUITING

Northwestern Memorial Hospital

Chicago, Illinois, United States

Site Status RECRUITING

Second Affiliated Hospital of Zhejiang University

Hangzhou, , China

Site Status RECRUITING

Bucheon Sejong Hospital

Bucheon-si, , South Korea

Site Status ACTIVE_NOT_RECRUITING

Chungnam National University Hospital

Daejeon, , South Korea

Site Status RECRUITING

Asan Medical Center

Seoul, , South Korea

Site Status RECRUITING

Seoul National University Hospital

Seoul, , South Korea

Site Status COMPLETED

Countries

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United States China South Korea

Central Contacts

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Duk-woo Park, MD

Role: CONTACT

82230103995

Do-yoon Kang, MD

Role: CONTACT

Facility Contacts

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Alan Ching Yuen Yeung, MD

Role: primary

James D. Flaherty, MD

Role: primary

Jian-an Wang, MD

Role: primary

Jae-hyung Park, MD

Role: primary

Duk-woo Park, MD

Role: primary

References

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Kim M, Kang DY, Ahn JM, Kim JB, Yeung AC, Nishi T, Fearon WF, Cantey EP, Flaherty JD, Davidson CJ, Malaisrie SC, Kim HJ, Lee J, Park J, Kim H, Cho S, Choi Y, Park SJ, Park DW. Sex-Specific Disparities in Clinical Outcomes After Transcatheter Aortic Valve Replacement Among Different Racial Populations. JACC Asia. 2024 Feb 13;4(4):292-302. doi: 10.1016/j.jacasi.2023.11.016. eCollection 2024 Apr.

Reference Type DERIVED
PMID: 38660112 (View on PubMed)

Kim H, Kang DY, Ahn JM, Kim JB, Yeung AC, Nishi T, Fearon WF, Cantey EP, Flaherty JD, Davidson CJ, Malaisrie SC, Kim N, Kim M, Lee J, Park J, Choi Y, Park SJ, Park DW. Race-Specific Impact of Conventional Surgical Risk Score on 1-Year Mortality After Transcatheter Aortic Valve Replacement. JACC Asia. 2023 Feb 28;3(3):376-387. doi: 10.1016/j.jacasi.2022.11.007. eCollection 2023 Jun.

Reference Type DERIVED
PMID: 37323869 (View on PubMed)

Kang DY, Ahn JM, Kim JB, Yeung A, Nishi T, Fearon W, Cantey EP, Flaherty JD, Davidson CJ, Malaisrie SC, Park SY, Yun SC, Ko E, Park H, Lee SA, Kim DH, Kim HJ, Kim JB, Choo SJ, Park DW, Park SJ. Inter-racial differences in patients undergoing transcatheter aortic valve implantation. Heart. 2022 Sep 12;108(19):1562-1570. doi: 10.1136/heartjnl-2021-320364.

Reference Type DERIVED
PMID: 35110384 (View on PubMed)

Park H, Ahn JM, Kang DY, Kim JB, Yeung AC, Nishi T, Fearon WF, Cantey EP, Flaherty JD, Davidson CJ, Malaisrie SC, Kim S, Yun SC, Ko E, Lee SA, Kim DH, Kim HJ, Kim JB, Choo SJ, Park DW, Park SJ. Racial Differences in the Incidence and Impact of Prosthesis-Patient Mismatch After Transcatheter Aortic Valve Replacement. JACC Cardiovasc Interv. 2021 Dec 27;14(24):2670-2681. doi: 10.1016/j.jcin.2021.08.038. Epub 2021 Nov 24.

Reference Type DERIVED
PMID: 34838464 (View on PubMed)

Other Identifiers

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AMCCV2019-01

Identifier Type: -

Identifier Source: org_study_id

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