Trial Outcomes & Findings for Intramuscular Heating Rates of a Chattanooga Intelect XT Therapeutic Ultrasound (NCT NCT03816709)

NCT ID: NCT03816709

Last Updated: 2021-05-27

Results Overview

A thermocouple was inserted at the 1 cm depth to determine the tissue temperatures.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

25 participants

Primary outcome timeframe

Baseline to end of treatment (up to 15 minutes or until temperatures increased 4 degrees, which occurred at 6 minutes)

Results posted on

2021-05-27

Participant Flow

Twenty-five subjects were recruited through the Institution's Listserve from January-February, 2019.

Participant milestones

Participant milestones
Measure
Therapeutic Ultrasound Treatment
All subjects received a therapeutic ultrasound treatment with the Chattanooga Intelect Legend XT machine with the following parameters: 3 MHz, 1.0 W/cm2, 15 minute treatment time. Therapeutic Ultrasound: A therapeutic ultrasound treatment was applied to the left medial gastrocnemius muscle with the following parameters: 3 MHz, 1.0 W/cm2 for 15 minutes.
Overall Study
STARTED
25
Overall Study
COMPLETED
25
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Therapeutic Ultrasound Treatment
n=25 Participants
All subjects received a therapeutic ultrasound treatment with the Chattanooga Intelect Legend XT machine with the following parameters: 3 MHz, 1.0 W/cm2, 15 minute treatment time. Therapeutic Ultrasound: A therapeutic ultrasound treatment was applied to the left medial gastrocnemius muscle with the following parameters: 3 MHz, 1.0 W/cm2 for 15 minutes.
Age, Categorical
<=18 years
0 Participants
n=25 Participants
Age, Categorical
Between 18 and 65 years
25 Participants
n=25 Participants
Age, Categorical
>=65 years
0 Participants
n=25 Participants
Sex: Female, Male
Female
14 Participants
n=25 Participants
Sex: Female, Male
Male
11 Participants
n=25 Participants
Region of Enrollment
United States
25 participants
n=25 Participants

PRIMARY outcome

Timeframe: Baseline to end of treatment (up to 15 minutes or until temperatures increased 4 degrees, which occurred at 6 minutes)

Population: Intent to treat population. All subjects received the Ultrasound treatment with a thermocouple recording tissue temperatures at the 1 cm depth.

A thermocouple was inserted at the 1 cm depth to determine the tissue temperatures.

Outcome measures

Outcome measures
Measure
Therapeutic Ultrasound Treatment
n=25 Participants
All subjects received a therapeutic ultrasound treatment with the Chattanooga Intelect Legend XT machine with the following parameters: 3 MHz, 1.0 W/cm2, 15 minute treatment time. Therapeutic Ultrasound: A therapeutic ultrasound treatment was applied to the left medial gastrocnemius muscle with the following parameters: 3 MHz, 1.0 W/cm2 for 15 minutes at the depths of 1.0, 1.75, and 2.5 cm.
Heating Rate at 1 cm Depth
6.49 degrees Celcius
Standard Deviation 1.24

PRIMARY outcome

Timeframe: Baseline to end of treatment (up to 15 minutes or until temperatures increased 4 degrees, which occurred at 8 minutes)

Population: Intent to treat. All subject received the Ultrasound treatment with a thermocouple at the 1.75 cm depth to determine tissue temperature

A thermocouple was inserted at the 1.75 cm depth to determine the tissue temperatures.

Outcome measures

Outcome measures
Measure
Therapeutic Ultrasound Treatment
n=25 Participants
All subjects received a therapeutic ultrasound treatment with the Chattanooga Intelect Legend XT machine with the following parameters: 3 MHz, 1.0 W/cm2, 15 minute treatment time. Therapeutic Ultrasound: A therapeutic ultrasound treatment was applied to the left medial gastrocnemius muscle with the following parameters: 3 MHz, 1.0 W/cm2 for 15 minutes at the depths of 1.0, 1.75, and 2.5 cm.
Heating Rate at 1.75 cm Depth
5.50 degrees Celcius
Standard Deviation 1.34

PRIMARY outcome

Timeframe: Baseline to end of treatment (up to 15 minutes or until temperatures increased 4 degrees, which did not occur in the 15 minute treatment)

Population: Intent to treat. All subjects received the Ultrasound treatment with a thermocouple at the 2.5 cm depth to determine tissue temperatures.

A thermocouple was inserted at the 2.5 cm depth to determine the tissue temperatures.

Outcome measures

Outcome measures
Measure
Therapeutic Ultrasound Treatment
n=25 Participants
All subjects received a therapeutic ultrasound treatment with the Chattanooga Intelect Legend XT machine with the following parameters: 3 MHz, 1.0 W/cm2, 15 minute treatment time. Therapeutic Ultrasound: A therapeutic ultrasound treatment was applied to the left medial gastrocnemius muscle with the following parameters: 3 MHz, 1.0 W/cm2 for 15 minutes at the depths of 1.0, 1.75, and 2.5 cm.
Heating Rate at 2.5 cm Depth
3.07 degrees Celcius
Standard Deviation 1.53

Adverse Events

Therapeutic Ultrasound Treatment

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Kara Gange, Associate Professor

North Dakota State University

Phone: 701-231-5777

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place