Evaluation of the SmartBx System for Breast Biopsy

NCT ID: NCT03808116

Last Updated: 2020-11-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-06-10

Study Completion Date

2019-09-01

Brief Summary

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Performance evaluation of a novel, semi-automated device and method for needle core biopsy download compared to standard methods in terms of:

3\. Biopsy core length obtained (i.e. collecting all tissue fragments) 4. Biopsy core yield (i.e. percent of tissue loss during the pathologic processing)

Detailed Description

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Examination procedure:

* Biopsy cores will be collected from the breast during US guided biopsy procedure.
* The number of cores taken will be decided per the physician discretion according to the clinical demand.
* Additional two biopsy core will be taken the SmartBx cassette. Since the SmartBx cassette holds two biopsies together, two consecutive cores will be collected using the SmartBx.
* samples will be photographed for measurements in 2 steps during the process:

1. On the needle notch \[A\].
2. On the glass slide \[B\].
* Standard tissue fixation, processing of the samples in paraffin will be performed unchanged per the pathology laboratory protocols.
* Embedding of the biopsy cores taken with the SmartBx will be embedded using the SmartBx mold and tamper.
* Standard staining and histology analysis will be preformed to the sectioned samples, unchanged per the pathology protocols.

• Analysis will be preformed to the histological results, and a comparison between the standard procedures samples to the SmartBx samples will be performed in terms of -
* Biopsy core length obtained (i.e. collecting all tissue fragments)
* Biopsy core yield (i.e. percent of tissue loss during the pathologic processing)

Conditions

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Breast Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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SmartBx biopsy collection

* Biopsy cores will be collected from the breast during US guided biopsy procedure.
* The number of cores taken will be decided per the physician discretion according to the clinical demand.
* Additional two biopsy core will be taken the SmartBx cassette

Group Type EXPERIMENTAL

SmartBx

Intervention Type DEVICE

he SmartBx device is intended for the retention of a biopsy specimen and for preservation of the specimen's in-needle location and orientation.

The SmartBx is used as an aiding tool in biopsy procedures. When operated in conjunction with the standard equipment in a prostate biopsy procedure, the SmartBx may be used for the following:

* To preserve sample unity, including core fragments in their original location along the needle notch.
* Avoid sample damaging during sample removal from the needle and the following pathology process.

Interventions

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SmartBx

he SmartBx device is intended for the retention of a biopsy specimen and for preservation of the specimen's in-needle location and orientation.

The SmartBx is used as an aiding tool in biopsy procedures. When operated in conjunction with the standard equipment in a prostate biopsy procedure, the SmartBx may be used for the following:

* To preserve sample unity, including core fragments in their original location along the needle notch.
* Avoid sample damaging during sample removal from the needle and the following pathology process.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age 18 years or older
* Planned for breast biopsy procedure.
* Signed informed consent.

Exclusion Criteria

o Patient's unwilling to participate.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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UC Care, Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Haemek medical center

Afula, North Region, Israel

Site Status

Countries

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Israel

Other Identifiers

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EMC-0124-18

Identifier Type: -

Identifier Source: org_study_id