Synergistic Effects of Anxiety and Alcohol Use Among Latinos and Its Sociocultural Mechanisms

NCT ID: NCT03807817

Last Updated: 2024-02-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

99 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-01

Study Completion Date

2024-01-31

Brief Summary

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The purpose of this study is to examine the pharmacological effects of alcohol on acute anxiety levels in a sample of Latino drinkers, and cultural experiences influencing these relationships.

Detailed Description

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Conditions

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Alcohol Drinking Racism

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Moderate Alcohol

Group Type EXPERIMENTAL

Alcohol administration

Intervention Type OTHER

Amount of alcohol to be administered.

Low Alcohol

Group Type EXPERIMENTAL

Alcohol administration

Intervention Type OTHER

Amount of alcohol to be administered.

Placebo Alcohol

Group Type ACTIVE_COMPARATOR

Placebo

Intervention Type OTHER

Placebo Alcohol

No Alcohol

Group Type ACTIVE_COMPARATOR

No Alcohol

Intervention Type OTHER

No Alcohol

Interventions

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Alcohol administration

Amount of alcohol to be administered.

Intervention Type OTHER

Placebo

Placebo Alcohol

Intervention Type OTHER

No Alcohol

No Alcohol

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. 21-65 years of age
2. moderate or heavy drinker based on a past-month AUDIT score \>= 8.

Exclusion Criteria

1. Possibility of being pregnant (verified by urine sample);
2. Self-reported history of or treatment for alcohol/other drug problems (as required by the IRB in past human alcohol administration research);
3. Moderate risk for drug problems as indicated by SMAST scores ≥ 5 or ASSIST scores of ≥ 4 (see Measures);
4. Medical conditions that contraindicate the use of alcohol (e.g., diabetes, liver disease);
5. Current use of psychiatric meds or any meds with alcohol contraindication (e.g., antibiotics);
6. Current non-alcohol substance use disorder;
7. Active suicidality (i.e., suicidal ideation, intent, and/or plan) or current psychosis.
Minimum Eligible Age

21 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIH

Sponsor Role collaborator

University of Houston

OTHER

Sponsor Role lead

Responsible Party

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Andres G. Viana

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Andres G Viana, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

University of Houston

Locations

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University of Houston

Houston, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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1K23AA025920-01A1

Identifier Type: NIH

Identifier Source: org_study_id

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