Comparison of Scalp Microbiota of the Psoriasis and Seborrheic Dermatitis Patients

NCT ID: NCT03807453

Last Updated: 2020-09-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-04-25

Study Completion Date

2019-06-18

Brief Summary

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A sterile swap specimen taken from the scalp of the patients with psoriasis vulgaris or seborrheic dermatitis and the volunteer control group will be examined in our study. The examples of the microbiota of the patients will be taken both the lesional scalp and the lesion-free part of the scalp. Then, the microbiota differences between the lesioned scalp and the lesion-free scalp of both groups, and the microbiome differences between the two groups and the control group will be evaluated.

Detailed Description

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Conditions

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Psoriasis Vulgaris Seborrheic Dermatitis Microbial Colonization

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Psoriasis Vulgaris patients-Lesion

Microbiota

Intervention Type OTHER

The scalp microbiota

Psoriasis Vulgaris patients-Lesion free

Microbiota

Intervention Type OTHER

The scalp microbiota

Seborrheic Dermatitis-Lesion

Microbiota

Intervention Type OTHER

The scalp microbiota

Seborrheic Dermatitis-Lesion free

Microbiota

Intervention Type OTHER

The scalp microbiota

Control Group

Microbiota

Intervention Type OTHER

The scalp microbiota

Interventions

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Microbiota

The scalp microbiota

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Patients with scalp psoriasis
2. Patients with seborrheic dermatitis
3. Agree to participate in research 4 - Do not use any drugs for their disease topically or systemically for two months

Exclusion Criteria

1. Patients who do not want to participate in the study
2. Patients with psoriasis vulgaris or seborrheic dermatitis that does not effect scalp.
3. Those with chronic diseases that may affect skin microbiome
4. Patients using antibiotics, antifungal or antiviral therapy for any reason for the last one month.
5. Patients who are using topical or systemic drugs for their illness
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Turkish Dermatology Association

UNKNOWN

Sponsor Role collaborator

Istanbul Medeniyet University

OTHER

Sponsor Role lead

Responsible Party

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Melek Aslan Kayıran

Dermatologist, M.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Melek Aslan Kayıran

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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IstanbulMU2

Identifier Type: -

Identifier Source: org_study_id

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