Calculated and Graphically Produced Depth of Anesthesia

NCT ID: NCT03807271

Last Updated: 2019-12-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

114 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-01-14

Study Completion Date

2019-11-13

Brief Summary

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There are studies that suggest that unsatisfying levels of anesthesia can cause peri- and postoperative complications in the patient undergoing surgery. Having a unnecessary "deep" anesthesia level can be harmful, causing acute renal failure, injure to myocard, cause delirium and increase the mortality rate. Being too "light", on the other hand, can make the patient experience awareness when muscle relaxant is used. This can lead to serious psychological struggles.

Evaluating the depth of anesthesia is the most important task of the anesthesia team, but can be difficult because clinical signs depend on many factors. In addition to clinical evaluation, EEG is commonly used for interpreting the level of anesthesia in todays practice. Unfortunately, this method is not always accurate and has a delay.

New devices are now developed to calculate the anesthesia level based on the drugs given. The level is simultaneously presented graphically on screen. The purpose of this study is to investigate and compare clinical parameters within patients undergoing general anesthesia, with and without the use of such devices. Hemodynamic stability, less use of adrenergics, higher EEG-levels, a more rapid wake-up and shorter time in post operative care can indicate a more precise level of anesthesia, hence, promote patient safety.

Detailed Description

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Conditions

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Anesthesia, General

Keywords

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Anesthesia, Methods Anesthesia, Analysis Patient Safety Anesthetics/administration and dosage

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants
The anesthesia team must know if the anesthesia will be given by standard procedure or guided by the calculating device in addition.

Study Groups

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Smart Pilot(R) View

Anesthesia provided by standard procedure, additionally guided by Smart Pilot(R) View, a device with calculated and graphically produced depth of anesthesia.

Group Type EXPERIMENTAL

Calculated and graphically produced depth of anesthesia (Smart Pilot® View)

Intervention Type DEVICE

Smart Pilot® View is a device integrated in the ventilator used under general anesthesia. The depth of anesthesia is calculated based on age, weight, height and the medication given - both volatiles and intravenous. The device does not control the supply of medication directly, but provides an estimate of anesthesia depth that can help the anesthesia team to control the supply of anesthetic agents under general anesthesia, ie indirectly.

Standard

Anesthesia provided by standard procedure.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Calculated and graphically produced depth of anesthesia (Smart Pilot® View)

Smart Pilot® View is a device integrated in the ventilator used under general anesthesia. The depth of anesthesia is calculated based on age, weight, height and the medication given - both volatiles and intravenous. The device does not control the supply of medication directly, but provides an estimate of anesthesia depth that can help the anesthesia team to control the supply of anesthetic agents under general anesthesia, ie indirectly.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* ASA 1-3
* Standard premedication
* General anesthesia, total intravenous anesthesia

Exclusion Criteria

* Alcoholics
* BMI 35 or higher
* Unable to give consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Sykehuset Innlandet HF

OTHER

Sponsor Role collaborator

Norwegian University of Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Heidi Vifladt, MD

Role: STUDY_DIRECTOR

Norwegian University of Science and Technology

Locations

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Anestesiavdeling Lillehammer Sykehus

Lillehammer, Oppland, Norway

Site Status

Countries

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Norway

References

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Strand H, Elshaug AC, Bernersen O, Ballangrud R. Effectiveness of the advisory display SmartPilot(R) view in the assessment of anesthetic depth in low risk gynecological surgery patients: a randomized controlled trial. BMC Anesthesiol. 2022 Feb 28;22(1):57. doi: 10.1186/s12871-022-01593-w.

Reference Type DERIVED
PMID: 35227197 (View on PubMed)

Other Identifiers

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2018/2176

Identifier Type: -

Identifier Source: org_study_id