Associations of Nighttime Light Exposure During Pregnancy With Neonatal Jaundice：a Multi-centre Prospective Study in China

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

2977 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-02-01

Study Completion Date

2019-12-31

Brief Summary

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Make a neonatal jaundiced nomogram on Chinese jaundice data by joinning the major neonate centers all around China.

Detailed Description

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This was a multi-centre prospective study. All infants included were born in 8 hospitals in the southern, eastern, northern, western and central regions of mainland China in 2019. A total of 20839 transcutaneous bilirubin(TCB) measurements were performed with 2977 neonates at designated time points. The mean NTL exposure during pregnancy was respectively calculated based on each participant's residential address over the study course. The primary outcome was whether the neonate was diagnosed with hyperbilirubinemia within the first seven days of life. The effect of maternal nocturnal light exposure on neonate jaundice analyzed with lasso regression and random forest machine learning methods.

Conditions

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Jaundice, Neonatal

Study Design

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Observational Model Type

OTHER

Study Time Perspective

OTHER

Study Groups

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neonate

transcutaneous bilirubin(TCB) measurements were performed with 2977 neonates at designated time points. The mean NTL exposure during pregnancy was respectively calculated based on each participant's residential address over the study course.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

gestational age more than 35 weeks(≥35) -

Exclusion Criteria

all kinds of congenital diseases, infants with pathologic jaundice

\-

Minimum Eligible Age

1 Day

Maximum Eligible Age

7 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Responsible Party

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yang jie

Director of neonatology of GuangdongWCH

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Jie Yang

Guangzhou, Guangdong, China

Site Status

Countries

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China

Other Identifiers

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Guangdong WCH

Identifier Type: -

Identifier Source: org_study_id