A Trial Comparing Interpersonal Therapy to Exposure Therapy for PTSD Due to Military Sexual Trauma (MST) in Male and Female Military Personnel
NCT ID: NCT03803332
Last Updated: 2025-12-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
208 participants
INTERVENTIONAL
2020-03-09
2026-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Exposure Therapy
Participants receive 10 90-minute exposure therapy sessions for PTSD following the treatment procedures as outlined in the standard Prolonged Exposure therapy manual.
Exposure Therapy
Psychotherapy including imaginal and in vivo exposure for PTSD.
Interpersonal Psychotherapy
Participants receive 14 weekly 50-minute Interpersonal Psychotherapy sessions focused on the interpersonal sequelae of trauma in current daily life.
Interpersonal Psychotherapy
Psychotherapy that focuses on the effects of PTSD on current interpersonal functioning.
Interventions
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Exposure Therapy
Psychotherapy including imaginal and in vivo exposure for PTSD.
Interpersonal Psychotherapy
Psychotherapy that focuses on the effects of PTSD on current interpersonal functioning.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Military Sexual Trauma (MST) survivors, with MST defined as actual or threatened sexual violence, from Vietnam era to current Operation Iraqi Freedom/Operation Enduring Freedom/Operation New Dawn
* Diagnosed with PTSD consequent to MST, with a minimum CAPS score \> 40
* Medically stable at time of study enrollment (for persons with chronic injuries and that any disability present does not prevent attendance of weekly outpatient therapy sessions)
* Ability to provide informed consent and function at an intellectual level sufficient to allow accurate completion of all assessment instruments
* Stable on psychotropic medication for the prior 60 days
Exclusion Criteria
* Participation in a clinical trial or concurrent evidence-based treatment for MST-related psychiatric conditions or PTSD during the previous 3 months
* Current evidence of significant unstable medical illness or organic brain impairment such that the patient could not attend sessions regularly or complete assessments
* Patients who in the investigator's judgment pose a current homicidal or suicidal risk
* Current or history of substance dependence in the past 90 days.
18 Years
85 Years
ALL
No
Sponsors
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United States Department of Defense
FED
Weill Medical College of Cornell University
OTHER
Responsible Party
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Principal Investigators
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JoAnn Difede, PhD
Role: PRINCIPAL_INVESTIGATOR
Weill Medical College of Cornell University
Locations
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Weill Cornell Medicine
New York, New York, United States
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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W81XWH-16-R-BAA1
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
1409015511
Identifier Type: -
Identifier Source: org_study_id