D Mannose for Prevention and Treatment of RUTIs

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-01

Study Completion Date

2018-12-25

Brief Summary

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The aim of this review is to address clinical reliability, efficacy and safety of long-term treatment with oral D Mannose for the prevention of recurrent urinary tract infections (RUTIs) in females.

Detailed Description

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A comprehensive systematic MEDLINE, Embase, Cochrane search was performed for English language reports published before December 2018 using the term "recurrent urinary tract infections and d mannose." We searched Medline, Embase, and the Cochrane Register of Controlled Trials since January 2010 to December 2018. Eligible studies did not include non-oral therapy, local (vaginal) treatment in women with RUTIs.

Study eligibility criteria- We identified eligible original articles. The heterogeneity of the available studies, their different rationale and aim, the assumption of d mannose for prophylaxis or treatment of recurrent UTIs need to be taken into account.

Conditions

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Recurrent Urinary Tract Infections Antibiotic Prophylaxis Antibiotic Resistance

Keywords

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recurrent urinary tract infections d mannose prophylaxis antibiotic prophylaxis

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Interventions

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systematic review

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

recurrent urinary tract infections (RUTIs)

Exclusion Criteria

Upper urinary tract infections, severe clinical symptoms, fever \> 37,5 with lumbar pain

Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Daniele Porru

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Daniele Porru, MD

Role: PRINCIPAL_INVESTIGATOR

Fondazione IRCCS Policlinico San Matteo

Locations

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Urology Department Fondazione IRCCS Policlinico San Matteo

Pavia, , Italy

Site Status

Countries

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Italy

Other Identifiers

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ReviewUTIs

Identifier Type: -

Identifier Source: org_study_id