Herbal Tea in the Treatment of Type 2 Diabetes Mellitus

NCT ID: NCT03787563

Last Updated: 2018-12-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-01-01

Study Completion Date

2019-01-20

Brief Summary

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Diabetes mellitus is a chronic disease caused by inherited and/or acquired deficiency in production of insulin by the pancreas, or by the ineffectiveness of the insulin produced. It has become a major healthcare problem in India. High-quality, low-cost solutions adapted to the local context are critical to addressing the current crisis in the management of diabetes. Herbal tea consists of tulsi, guava and stevia, which has glucose lowering properties.The aim of this trial is to study the effect of a herbal tea in the glycemic response in the early type 2 diabetes.

Detailed Description

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Conditions

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Type 2 Diabetes Mellitus

Keywords

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Herbal Tea Diabetes

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

all the subjects will receive sequence of different study treatments.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

TRIPLE

Participants Caregivers Investigators
Double blinded study

Study Groups

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Active Herbal tea

One tea bag infusion three times a day each before breakfast, lunch and dinner.

Group Type ACTIVE_COMPARATOR

Herbal Tea

Intervention Type DRUG

All participants will be given the intervention in an infusion tea bag. Participant will be instructed to take one tea bag three times a day at before breakfast, lunch and dinner meals. At the time of randomization both active and placebo infusion bag will be provided.There will be one day of washout period after 2 days on treatment.

Placebo Tea

Similar looking tea bag infusion three times a day each before breakfast, lunch and dinner.

Group Type PLACEBO_COMPARATOR

Placebo Tea

Intervention Type DRUG

Similar looking inert placebo tea.

Interventions

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Herbal Tea

All participants will be given the intervention in an infusion tea bag. Participant will be instructed to take one tea bag three times a day at before breakfast, lunch and dinner meals. At the time of randomization both active and placebo infusion bag will be provided.There will be one day of washout period after 2 days on treatment.

Intervention Type DRUG

Placebo Tea

Similar looking inert placebo tea.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

Adults aged over 18 years and having a diagnosis of diabetes and meeting one of the following criteria

1. Fasting Plasma Glucose ≥126 mg/dL, fasting defined as no caloric intake for at least 8 hours, AND
2. 2-h Post load Glucose ≥140 mg/dL during an OGTT. AND
3. Glycosylated haemoglobin (A1C) ≥ 6.5 %.

Exclusion Criteria

Any one of the following

1. Patients on Insulin therapy.
2. Patients on oral hypoglycemic agents other than metformin
3. Any history suggestive of micro vascular or macro vascular disease - coronary artery disease, stroke, peripheral artery disease or diabetes related retinal changes.
4. Women in child bearing age unable to practice any form of contraception
5. Patients with diagnosis of Anaemia (Hemoglobin \<11 g/dl in Female and \<13 g/dl in Male)
6. Impaired renal function; estimated glomerular function \<60mls/min/1.73m2.
7. Known history of any chronic illness taking regular pharmacological agents.
8. Blood pressure fluctuations exceeding 20 mmHg on 2 subsequent clinic visits or known history of hypotension or bradycardia in last 6 months or taking 3 or more antihypertensive medications regularly in the last 6 weeks
9. Known history of autonomic dysfunction like diabetic autonomic neural imbalance or neuropathy
10. Participating in another clinical trial with an active intervention or drug or device with last dose taken within 60 days.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Composite Interceptive Med-Science Laboratories Pvt Ltd

UNKNOWN

Sponsor Role collaborator

Composite Interceptive Med Science

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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HD Ramachandra Prabhu, MBBS, MD

Role: PRINCIPAL_INVESTIGATOR

Health India Hospital

Locations

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Health India Hospital

Bangalore, Karnataka, India

Site Status

Countries

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India

Central Contacts

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Sanjaya Chauhan, Pharm.D

Role: CONTACT

Phone: 09611252350

Email: [email protected]

Facility Contacts

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Thirumalesha RL, BAMS

Role: primary

Other Identifiers

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CIMED - 001- 2018

Identifier Type: -

Identifier Source: org_study_id