Feasibility of Web-based CBT-I Intervention in Individuals With Multiple Sclerosis

NCT ID: NCT03783585

Last Updated: 2019-08-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-10-01

Study Completion Date

2019-08-20

Brief Summary

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Forty individuals with multiple sclerosis (MS) will be randomly assigned to a 6-week web-based cognitive behavior therapy for insomnia intervention (wCBT-I) or to wCBT-I plus biweekly support meetings with research personnel via phone or video. Questionnaires will be used to assess sleep quality, fatigue, and satisfaction. Recruitment, retention, attrition, adherence, and safety information will also be collected. This study is significant because addressing insomnia symptoms through CBT-I could be a low-cost, low-risk, non-pharmacological options for improving sleep quality and MS symptoms in individuals with MS. This study is innovative because CBT-I has never been delivered via a web-based application to individuals with MS which may increase access to services.

Detailed Description

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Conditions

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Multiple Sclerosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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cognitive behavioral therapy for insomnia (CBT-I)

Participants randomized to this arm will participate in a 6-week web-based cognitive behavioral therapy for insomnia (CBT-I) program.

Group Type EXPERIMENTAL

Cognitive behavioral therapy for insomnia

Intervention Type BEHAVIORAL

The web-based CBT-I program is a 6-week interactive, online program that delivers typical CBT-I treatment techniques of stimulus control, sleep restriction, behavioral modifications, and cognitive restructuring.

CBT-I + biweekly support

Participants randomized to this arm will participate in a 6-week web-based CBT-I program. In addition, biweekly support consisting of one-on-one, semi-structured, online video-chat sessions (via HIPAA-compliant Zoom) or phone calls will be conducted every other week.

Group Type EXPERIMENTAL

Cognitive behavioral therapy for insomnia

Intervention Type BEHAVIORAL

The web-based CBT-I program is a 6-week interactive, online program that delivers typical CBT-I treatment techniques of stimulus control, sleep restriction, behavioral modifications, and cognitive restructuring.

Cognitive behavioral therapy for insomnia + biweekly support

Intervention Type BEHAVIORAL

Individuals randomized into the CBT-I + biweekly support will participate in CBT-I as described as well as a biweekly phone call or video call with research personnel for motivational interviewing.

Interventions

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Cognitive behavioral therapy for insomnia

The web-based CBT-I program is a 6-week interactive, online program that delivers typical CBT-I treatment techniques of stimulus control, sleep restriction, behavioral modifications, and cognitive restructuring.

Intervention Type BEHAVIORAL

Cognitive behavioral therapy for insomnia + biweekly support

Individuals randomized into the CBT-I + biweekly support will participate in CBT-I as described as well as a biweekly phone call or video call with research personnel for motivational interviewing.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* 18-80 years old
* diagnosis of MS by physician
* report of difficulty falling asleep, maintaining sleep, or waking up too early at least 3 nights/week for the past 6 months
* ≥10 on Insomnia Severity Index (ISI)
* English speaking
* reports access to internet service and phone
* has a high school diploma to serve as a proxy measurement of reading ability to ensure adequate reading ability to participate in the study.

Exclusion Criteria

* known untreated sleep disorder (such as sleep apnea or restless leg syndrome)
* \>3 on STOP BANG indicating risk of sleep apnea
* increased risk of restless leg syndrome
* nervous system disorder other than MS
* relapse and/or corticosteroid use in past 8 weeks
* score of ≥15 on the Patient Health Questionnaire (PHQ-9) indicating severe depression or endorse any suicidal ideation (answer 1, 2 or 3 on #9 of the PHQ-9)
* performs shift-work.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Kansas Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Catherine Siengsukon, PT, PhD

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Catherine Siengsukon, PT, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Kansas Medical Center

Locations

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Catherine Siengsukon

Kansas City, Kansas, United States

Site Status

Countries

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United States

Other Identifiers

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STUDY00142464

Identifier Type: -

Identifier Source: org_study_id

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