Lenalidomide Adherence in Older Adults

NCT ID: NCT03779555

Last Updated: 2020-10-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

17 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-12-13

Study Completion Date

2020-08-31

Brief Summary

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To describe patterns of adherence and pilot baseline measures to investigate factors associated with lower adherence to lenalidomide in older adults with myeloma.

Detailed Description

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Conditions

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Multiple Myeloma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients taking lenalidomide for multiple myeloma

-Patients will be seen at baseline, 1 month (+/- 1 week), 2 months (3-5 weeks following 1-month assessment), and 3 months (3-5 weeks after 2-month follow-up)

Medication Event Monitoring System

Intervention Type OTHER

-Microchipped bottle cap

Interventions

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Medication Event Monitoring System

-Microchipped bottle cap

Intervention Type OTHER

Other Intervention Names

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MEMS

Eligibility Criteria

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Inclusion Criteria

* Age ≥65
* Receiving lenalidomide for treatment of multiple myeloma.
* Anticipated to receive ongoing care at Siteman Cancer Center and its satellite sites
* Able to read and understand English.
* Able to understand and willing to sign an IRB-approved written informed consent document.

Exclusion Criteria

* Estimated life expectancy \<6 months.
* Anticipated duration of lenalidomide therapy \<3 months.
* Residing in a nursing facility where their medications are administered to them OR patient reports they do not self-administer their own medications.
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alliance for Clinical Trials in Oncology

OTHER

Sponsor Role collaborator

Washington University School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mark A Fiala, MSW

Role: PRINCIPAL_INVESTIGATOR

Washington University School of Medicine

Locations

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Washington University School of Medicine

St Louis, Missouri, United States

Site Status

Countries

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United States

References

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Silberstein AE, Fiala MA, Loh KP, Cordner T, Mian H, Wildes TM. A pilot study of adherence to lenalidomide among older patients with multiple myeloma. J Geriatr Oncol. 2023 Sep;14(7):101560. doi: 10.1016/j.jgo.2023.101560. Epub 2023 Jun 27. No abstract available.

Reference Type DERIVED
PMID: 37380519 (View on PubMed)

Related Links

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http://www.siteman.wustl.edu

Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine

Other Identifiers

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201812141

Identifier Type: -

Identifier Source: org_study_id

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