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Adrenal Venous Sampling Via an Antecubital Approach

NCT ID: NCT03778645

Last Updated: 2018-12-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-07-01

Study Completion Date

2018-12-31

Brief Summary

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Currently, adrenal venous sampling (AVS) serves as the gold standard for subtyping of PA. Right adrenal vein catheterization is often difficult due to unfavorable anatomy of the vein including small vein size, short length, caudal direction for the transfemoral approach, and rare drainage to the accessory hepatic vein. All of these factors limit the widespread use of this approach. Given that the right adrenal vein is angled caudally in most patients, AVS via an antecubital approach was performed since January 2012. The purpose of this multicenter retrospective study was to evaluate the safety and feasibility of AVS via the antecubital approach.

Detailed Description

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Primary aldosteronism (PA) is recognized as the most common cause of secondary hypertension, with a prevalence of approximately 10% among unselected hypertensive populations. Subtype diagnosis is crucial because unilateral primary aldosteronism can be treated by laparoscopic adrenalectomy or open surgery, which may result in a cure or significant improvement of blood pressure, thus decreases the incidence of cardio-cerebrovascular complications. Currently, adrenal venous sampling (AVS) serves as the gold standard for subtyping of PA. Given that the right adrenal vein is angled caudally in most patients, AVS via an antecubital approach was performed since January 2012 at the Fuwai Hospital. So far, there have been more than fifteen hospitals to have some experience on AVS via antecubital approach with investigators' helps. The purpose of this multicenter retrospective study was to evaluate the safety and feasibility of AVS via the antecubital approach.

Conditions

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Hyperaldosteronism Angiography

Keywords

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Adrenal venous sampling Hyperaldosteronism Angiography Antecubital approach

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Adrenal Venous Sampling

Adrenal Venous Sampling via an Antecubital Approach

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Consent of the principal investigator to participate to the data collection of patients with primary aldosteronism underwent AVS via antecubital approach

Exclusion Criteria

* Refusal of the principal investigator to participate to the AVSA Study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chinese Academy of Medical Sciences, Fuwai Hospital

OTHER

Sponsor Role lead

Responsible Party

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Xiongjing Jiang

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Xiongjing Jiang, MD

Role: PRINCIPAL_INVESTIGATOR

Fuwai Hospital, National Center for Cardiovascular Disease

Locations

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Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College

Beijing, Beijing Municipality, China

Site Status RECRUITING

The First Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China

Site Status RECRUITING

The Eighth Affiliated Hospital of Sun Yat-sen University

Shenzhen, Guangdong, China

Site Status RECRUITING

The First Affiliated Hospital of Guangxi Medical University

Nanning, Guangxi, China

Site Status RECRUITING

Henan Provincial People's Hospital

Zhengzhou, Henan, China

Site Status RECRUITING

The Second Affiliated Hospital of Nanchang University

Nanchang, Jiangxi, China

Site Status RECRUITING

The Second Hospital of Dalian Medical University

Dalian, Liaoning, China

Site Status RECRUITING

Ruijin Hospital, Shanghai Jiaotong University School of Medicine

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

Xi'an NO.3 Hospital

Xi’an, Shanxi, China

Site Status RECRUITING

The First Affiliated Hospital of Medical College of Shihezi Universtiy

Shihezi, Xinjiang, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Xiongjing Jiang, MD

Role: CONTACT

Phone: +861088322385

Email: [email protected]

Hui Dong, MD

Role: CONTACT

Phone: +861088322385

Email: [email protected]

Facility Contacts

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Xiongjing Jiang, MD

Role: primary

Qifu Li, MD

Role: primary

Nan Jia, MD

Role: primary

Jianling Li, MD

Role: primary

Min Liu, MD

Role: primary

Yifei Dong, MD

Role: primary

Ying Zhang, MD

Role: primary

Jianzhong Xu, MD

Role: primary

Kang Cheng, MD

Role: primary

Zhitao Yan, MD

Role: primary

References

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Dong H, Huang J, Zhang Y, Dong Y, Liu M, Yan Z, Li J, Chen Y, Zou Y, Wang J, Kang Y, Jiang Z, Song W, Zuo Y, Xiong H, Xu J, Jiang X. Adrenal Venous Sampling Via an Antecubital Approach in Primary Aldosteronism: A Multicenter Study. J Clin Endocrinol Metab. 2023 Dec 21;109(1):e274-e279. doi: 10.1210/clinem/dgad433.

Reference Type DERIVED
PMID: 37466201 (View on PubMed)

Other Identifiers

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2018-995

Identifier Type: -

Identifier Source: org_study_id