Defining the Sympathetic Skin Response of Migraineurs in the Facial Area
NCT ID: NCT03772860
Last Updated: 2018-12-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
70 participants
OBSERVATIONAL
2018-12-31
2019-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Healthy volunteers
Healthy volunteers will be exposed to pain stimulation, visual stimulation, auditory stimulation and mental stress
Pain stimulation
Pain will be simulated with an electric shock 25 mlAMP over the median nerve
Visual stimulation
Visual stimulation will be performed by a flicker of light on a computer screen at 15 Hrz for 0.3 seconds
Auditory stimulation
Auditory stimulation will be delivered through headphones with a sound at 500 Hrz at 85 decibels for 0.3 seconds
Mental stress
A mathematical challenge will be displayed on a computer screen that must be quickly solved
Left headache
Migraine patients with mostly left sided headache will be exposed to pain stimulation, visual stimulation, auditory stimulation and mental stress
Pain stimulation
Pain will be simulated with an electric shock 25 mlAMP over the median nerve
Visual stimulation
Visual stimulation will be performed by a flicker of light on a computer screen at 15 Hrz for 0.3 seconds
Auditory stimulation
Auditory stimulation will be delivered through headphones with a sound at 500 Hrz at 85 decibels for 0.3 seconds
Mental stress
A mathematical challenge will be displayed on a computer screen that must be quickly solved
Right headache
Migraine patients with mostly right sided headache will be exposed to pain stimulation, visual stimulation, auditory stimulation and mental stress
Pain stimulation
Pain will be simulated with an electric shock 25 mlAMP over the median nerve
Visual stimulation
Visual stimulation will be performed by a flicker of light on a computer screen at 15 Hrz for 0.3 seconds
Auditory stimulation
Auditory stimulation will be delivered through headphones with a sound at 500 Hrz at 85 decibels for 0.3 seconds
Mental stress
A mathematical challenge will be displayed on a computer screen that must be quickly solved
Bilateral headache
Migraine patients without a dominant side headache will be exposed to pain stimulation, visual stimulation, auditory stimulation and mental stress
Pain stimulation
Pain will be simulated with an electric shock 25 mlAMP over the median nerve
Visual stimulation
Visual stimulation will be performed by a flicker of light on a computer screen at 15 Hrz for 0.3 seconds
Auditory stimulation
Auditory stimulation will be delivered through headphones with a sound at 500 Hrz at 85 decibels for 0.3 seconds
Mental stress
A mathematical challenge will be displayed on a computer screen that must be quickly solved
Interventions
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Pain stimulation
Pain will be simulated with an electric shock 25 mlAMP over the median nerve
Visual stimulation
Visual stimulation will be performed by a flicker of light on a computer screen at 15 Hrz for 0.3 seconds
Auditory stimulation
Auditory stimulation will be delivered through headphones with a sound at 500 Hrz at 85 decibels for 0.3 seconds
Mental stress
A mathematical challenge will be displayed on a computer screen that must be quickly solved
Eligibility Criteria
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Inclusion Criteria
* Migraine patients according to ICH3 criteria
* Migraine patients with more than 1 attack per month
Exclusion Criteria
* Patients with hearing or visual decline
* Patients taking medication that effects the sympathetic system (except those taking beta blockers for migraine treatment)
18 Years
ALL
Yes
Sponsors
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Hillel Yaffe Medical Center
OTHER_GOV
Responsible Party
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Principal Investigators
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Yaron River, MD
Role: STUDY_DIRECTOR
Hillel Yaffe Medical Center
Locations
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Hillel Yaffe Medical Center
Hadera, , Israel
Countries
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Central Contacts
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Facility Contacts
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Erel Domany, MD
Role: primary
Other Identifiers
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HYMC-113-18
Identifier Type: -
Identifier Source: org_study_id