Topical Preparation of Pomegranate and Ginkgo Biloba for Anti-aging Activities
NCT ID: NCT03772418
Last Updated: 2018-12-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE1
30 participants
INTERVENTIONAL
2018-05-18
2020-02-28
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Cream base
A group of volunteers receiving placebo medications without natural extracts of ginkgo biloba and Pomegranate.
Cream Base
The formulated dosage form without ginkgo biloba or pomegranate will be applied to the 30 aging people who are suffering from wrinkles in the skin male and female. Typically, will be applied on two groups, one man (Group 0a) and one woman were (Group 0b) which they will be used plain cream.
Pomegrante and Ginkgo biloba group
A group of volunteers with the aging state receiving natural extracts of ginkgo biloba and Pomegranate in different topical dosage forms.
Pomegrante and Ginkgo biloba group
The extracts of ginkgo biloba and Pomegranate as formulated in topical dosage form will be applied to the 30 aging people who are suffering from wrinkles in the skin male and female. Formulated cream will be applied on two groups, one man (Group Ia)and one woman (Group Ib).
Interventions
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Cream Base
The formulated dosage form without ginkgo biloba or pomegranate will be applied to the 30 aging people who are suffering from wrinkles in the skin male and female. Typically, will be applied on two groups, one man (Group 0a) and one woman were (Group 0b) which they will be used plain cream.
Pomegrante and Ginkgo biloba group
The extracts of ginkgo biloba and Pomegranate as formulated in topical dosage form will be applied to the 30 aging people who are suffering from wrinkles in the skin male and female. Formulated cream will be applied on two groups, one man (Group Ia)and one woman (Group Ib).
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Follow up and collect data for a local and systemic activity of Ginkgo Biloba and Pomegranate
* The skin should be not injured as the cream can be easily applied
* Systemic oral capsule Ginkgo Biloba and Pomegranate can be also given to enhance the activity as anti-aging activity
Exclusion Criteria
* Hypertension disease
* Skin wound
50 Years
70 Years
ALL
Yes
Sponsors
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Ahmed A. H. Abdellatif
OTHER
Responsible Party
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Ahmed A. H. Abdellatif
Assistant Prof. at Pharmaceutics dept., Faculty of Pharmacy, Qassim University, KSA
Principal Investigators
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Ahmed Abdellatif, Ph.D.
Role: PRINCIPAL_INVESTIGATOR
Assistant Prof. at Pharmaceutics dept., Faculty of Pharmacy, Qassim University, KSA
Locations
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Assiut Clinic
Asyut, , Egypt
Faculty of Pharmacy
Buraidah, Al-Qassim Region, Saudi Arabia
Pharmaceutics dept., Faculty of Pharmacy, Qassim University
Buraidah, Al-Qassim Region, Saudi Arabia
Countries
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Central Contacts
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Facility Contacts
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Ahmed AH Abdellatif, PhD
Role: primary
Ahmed AH Abdellatif, Ph.D.
Role: primary
Ahmed AH Abdellatif, Ph.D.
Role: primary
References
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Dong LY, Fan L, Li GF, Guo Y, Pan J, Chen ZW. [Anti-aging action of the total lactones of ginkgo on aging mice]. Yao Xue Xue Bao. 2004 Mar;39(3):176-9. Chinese.
Kang SJ, Choi BR, Kim SH, Yi HY, Park HR, Song CH, Ku SK, Lee YJ. Beneficial effects of dried pomegranate juice concentrated powder on ultraviolet B-induced skin photoaging in hairless mice. Exp Ther Med. 2017 Aug;14(2):1023-1036. doi: 10.3892/etm.2017.4626. Epub 2017 Jun 16.
Rasul A, Akhtar N. Formulation and in vivo evaluation for anti-aging effects of an emulsion containing basil extract using non- invasive biophysical techniques. Daru. 2011;19(5):344-50.
Other Identifiers
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AlAzharPGB
Identifier Type: -
Identifier Source: org_study_id