Therapeutic Effect of the Low FODMAP Diet in Children With Functional Abdominal Pain.

NCT ID: NCT03771027

Last Updated: 2018-12-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

33 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-07-08

Study Completion Date

2017-12-08

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Diet components are important factors in pathogenesis of functional gastrointestinal disorders, especially in the irritable bowel syndrome. Fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) are a group of short chain, poorly absorbed and osmotically active carbohydrates, which can induce gastrointestinal symptoms because of rapid fermentation in different segments of the gut. Low FODMAP diet is a novel treatment option with proven efficacy in reducing symptoms of functional gastrointestinal disorders in adults. Conversely, although functional abdominal pain is a common health problem in children, the efficacy of a low FODMAP diet remains understudied in this population.

The aim of this study was to compare the effects of two diets: a low FODMAP diet and a diet based on standard dietary advice of the National Institute for Health and Care Excellence (NICE), on abdominal symptoms in children with functional abdominal pain.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Functional Abdominal Pain Syndrome

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

low FODMAP diet functional abdominal pain children

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Low FODMAP diet group

four weeks of the low FODMAP diet based on Monash University low FODMAP diet App.

Group Type EXPERIMENTAL

The low FODMAP diet.

Intervention Type OTHER

The low FODMAP group had reduced the intake of FODMAP. Children received 3 main meals and 2 snacks daily prepared by the catering company according to the Human Nutrition Recommendations for Polish Population. The dietary intervention lasted four weeks.

Control group

four weeks of the diet based on NICE guidelines and contained products with different FODMAP content

Group Type ACTIVE_COMPARATOR

The diet based on NICE guidelines.

Intervention Type OTHER

The control group based on NICE guidelines received diet contained products with different FODMAP content. Children received 3 main meals and 2 snacks daily prepared by the catering company according to the Human Nutrition Recommendations for Polish Population. The dietary intervention lasted four weeks.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

The low FODMAP diet.

The low FODMAP group had reduced the intake of FODMAP. Children received 3 main meals and 2 snacks daily prepared by the catering company according to the Human Nutrition Recommendations for Polish Population. The dietary intervention lasted four weeks.

Intervention Type OTHER

The diet based on NICE guidelines.

The control group based on NICE guidelines received diet contained products with different FODMAP content. Children received 3 main meals and 2 snacks daily prepared by the catering company according to the Human Nutrition Recommendations for Polish Population. The dietary intervention lasted four weeks.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* functional abdominal pain according to Rome III criteria
* consent to participate in the study
* positive decision of gastroenterologist concerning enrolment of the patient to the trial

Exclusion Criteria

* organic causes for gastrointestinal tract disorders,
* occurrence of an abdominal migraine, IBS, food allergies or intolerances, other significant disorders, acute infection
* antibiotic treatment within the last 8 weeks
Minimum Eligible Age

5 Years

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

National Science Centre, Poland

OTHER_GOV

Sponsor Role collaborator

University of Warmia and Mazury

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Katarzyna Boradyn

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Katarzyna M Boradyn, MSc

Role: PRINCIPAL_INVESTIGATOR

Department of Human Nutrition, Faculty of Food Science, University of Warmia and Mazury

Elżbieta Jarocka-Cyrta, Ph.D

Role: PRINCIPAL_INVESTIGATOR

Department of Pediatrics, Gastroenterology and Nutrition, Collegium Medicum Faculty of Medicine, University of Warmia and Mazury

Katarzyna E Przybyłowicz, Ph.D

Role: PRINCIPAL_INVESTIGATOR

Department of Human Nutrition, Faculty of Food Science, University of Warmia and Mazury

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Regional Specialized Children's Hospital

Olsztyn, , Poland

Site Status

University of Warmia and Mazury

Olsztyn, , Poland

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Poland

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2015/17/N/NZ5/02596

Identifier Type: -

Identifier Source: org_study_id