Statins and ARBs on Rheumatoid Activity

NCT ID: NCT03770702

Last Updated: 2018-12-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

PHASE3

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-10-01

Study Completion Date

2026-12-01

Brief Summary

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Investigational and comparative study between the anti-inflammatory effectof both angiotensin reeptor blockers and statins on rheumatoid arthritis disease activity on Egyptian patients

Detailed Description

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The study aims at ivestigating and comparing the anti-inflammatory effectof both angiotensin reeptor blockers and statins on rheumatoid arthritis disease activity on Egyptian patients

Conditions

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Rheumatoid Arthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Control group

No intervention

Group Type NO_INTERVENTION

No interventions assigned to this group

Angiotensin receptor blockers

ARB ( Angiotensin receptor blockers) + Traditional therpy.

Group Type ACTIVE_COMPARATOR

Angiotensin receptor blockers

Intervention Type DRUG

Candesartan

Statins

Statin + Traditional therapy.

Group Type ACTIVE_COMPARATOR

Statins

Intervention Type DRUG

Atorvastatin

Interventions

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Angiotensin receptor blockers

Candesartan

Intervention Type DRUG

Statins

Atorvastatin

Intervention Type DRUG

Other Intervention Names

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Cansartan Ator

Eligibility Criteria

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Inclusion Criteria

* Rheumatoid arthritis.

Exclusion Criteria

* Pregnant or lactating
* Hepatic or renal impairment.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sherief Abd-Elsalam

OTHER

Sponsor Role lead

Responsible Party

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Sherief Abd-Elsalam

Ass. Prof. Tropical Medicine

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Sahar K Hegazy, Prof

Role: PRINCIPAL_INVESTIGATOR

Head of Clinical Pharmacy Department

Tarek M Mostafa, Prof

Role: STUDY_DIRECTOR

Prof of Clinical Pharmacy

Emad M Elshebini, MD

Role: STUDY_CHAIR

Rheumatology Dept. - Menoufia University

Ahmed HM El-Abd, Msc

Role: STUDY_CHAIR

Clinical pharmacy Department-Tanta University

Locations

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Sherief Abd-Elsalam

Tanta, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Sherief Abd-Elsalam, Ph D

Role: CONTACT

Phone: 00201147773440

Email: [email protected]

Facility Contacts

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Ahmed El-Abd, Msc

Role: primary

Other Identifiers

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Rheumatoid

Identifier Type: -

Identifier Source: org_study_id