Trial Outcomes & Findings for A Stress Management and Resiliency Program for Adolescent and Young Adult Survivors (NCT NCT03768336)

NCT ID: NCT03768336

Last Updated: 2025-06-04

Results Overview

Percent of identified eligibles who were approached (hence given the opportunity to participate) who enroll (i.e., sign consent and complete baseline). Qualitative information from experts and participants will be used to inform feasibility.

Recruitment status

ACTIVE_NOT_RECRUITING

Study phase

NA

Target enrollment

72 participants

Primary outcome timeframe

Post-treatment completion (treatment is approximately 8 weeks)

Results posted on

2025-06-04

Participant Flow

As per our approved protocol, only individuals who signed consent and completed the baseline assessment were considered to be enrolled. Hence, 72 people met this criteria.

Participant milestones

Participant milestones
Measure
3RP Group Sessions
The 3RP-AYA will be delivered in weekly sessions over the course of approximately 8 weeks, for a total of 8 sessions immediately after enrollment.
Waitlist Control
The 3RP-AYA will be delivered in weekly sessions over the course of approximately 8 weeks, for a total of 8 sessions 2-months after enrollment.
Overall Study
STARTED
35
37
Overall Study
Baseline Completion
35
37
Overall Study
Remained Eligible
33
37
Overall Study
Program Initiation
29
35
Overall Study
Follow up Survey #1
29
35
Overall Study
Follow up Survey #2
29
34
Overall Study
COMPLETED
29
34
Overall Study
NOT COMPLETED
6
3

Reasons for withdrawal

Reasons for withdrawal
Measure
3RP Group Sessions
The 3RP-AYA will be delivered in weekly sessions over the course of approximately 8 weeks, for a total of 8 sessions immediately after enrollment.
Waitlist Control
The 3RP-AYA will be delivered in weekly sessions over the course of approximately 8 weeks, for a total of 8 sessions 2-months after enrollment.
Overall Study
Lost to Follow-up
3
2
Overall Study
Became Ineligible
2
0
Overall Study
Missed final survey (3-month follow-up)
1
0
Overall Study
Missed final survey (post-treatment
0
1

Baseline Characteristics

A Stress Management and Resiliency Program for Adolescent and Young Adult Survivors

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Enrolled Patients
n=72 Participants
All participants who consented and completed the baseline survey
Age, Continuous
23.76 years
STANDARD_DEVIATION 3.26 • n=5 Participants
Sex/Gender, Customized
Gender · Male
18 Participants
n=5 Participants
Sex/Gender, Customized
Gender · Female
53 Participants
n=5 Participants
Sex/Gender, Customized
Gender · Prefer not to describe
1 Participants
n=5 Participants
Race/Ethnicity, Customized
Race/ethnicity · Hispanic or Latino
15 Participants
n=5 Participants
Race/Ethnicity, Customized
Race/ethnicity · Asian
6 Participants
n=5 Participants
Race/Ethnicity, Customized
Race/ethnicity · Black or African American
3 Participants
n=5 Participants
Race/Ethnicity, Customized
Race/ethnicity · White
43 Participants
n=5 Participants
Race/Ethnicity, Customized
Race/ethnicity · Mixed Race
5 Participants
n=5 Participants
Months since treatment completion
18.82 months
STANDARD_DEVIATION 16.06 • n=5 Participants

PRIMARY outcome

Timeframe: Post-treatment completion (treatment is approximately 8 weeks)

Population: This consists of the total number of individuals who were eligible, were approached and informed about the study, and were offered the opportunity to participate.

Percent of identified eligibles who were approached (hence given the opportunity to participate) who enroll (i.e., sign consent and complete baseline). Qualitative information from experts and participants will be used to inform feasibility.

Outcome measures

Outcome measures
Measure
Total Individuals Approached
n=93 Participants
This consists of eligible individuals who were approached and informed about the study (thus had the opportunity to participate)
3RP-AYA Feasibility: Percent of Identified Eligibles Who Enroll
Enrolled
72 Participants
3RP-AYA Feasibility: Percent of Identified Eligibles Who Enroll
Active refusal
9 Participants
3RP-AYA Feasibility: Percent of Identified Eligibles Who Enroll
Passive refusal (made contact but never heard back)
10 Participants
3RP-AYA Feasibility: Percent of Identified Eligibles Who Enroll
Interested but unable to make groups
2 Participants

PRIMARY outcome

Timeframe: Post-treatment completion (treatment is approximately 8 weeks)

Population: Total number of patients who initiated the program.

Among those who initiated the program, this is the proportion of patients who completed the program (defined as completing 6 out of 8 sessions). Qualitative information from experts and participants will be used to inform feasibility.

Outcome measures

Outcome measures
Measure
Total Individuals Approached
n=64 Participants
This consists of eligible individuals who were approached and informed about the study (thus had the opportunity to participate)
3RP-AYA Feasibility: Proportion of Participants Completing the 3RP-AYA Program
Completed 6 out of 8 3RP-AYA sessions.
55 Participants
3RP-AYA Feasibility: Proportion of Participants Completing the 3RP-AYA Program
Completed less than 6 3RP-AYA
9 Participants

PRIMARY outcome

Timeframe: Post-treatment completion (treatment is approximately 8 weeks)

Population: These were inclusive of all responses to the acceptability items.

Acceptability will be assessed with five questions rated on a 4-point Likert scale (1=not at all to 4=very). Items will prompt participants to rate the extent to which they found the program to be enjoyable, helpful, applicable, convenient, and satisfaction. Qualitative information from experts and patients will also inform acceptability.

Outcome measures

Outcome measures
Measure
Total Individuals Approached
n=60 Participants
This consists of eligible individuals who were approached and informed about the study (thus had the opportunity to participate)
3RP-AYA Acceptability: Five Questions
How enjoyable was the program
3.62 units on a scale
Standard Deviation .69
3RP-AYA Acceptability: Five Questions
How helpful was the program?
3.45 units on a scale
Standard Deviation .75
3RP-AYA Acceptability: Five Questions
How relevant was the program?
3.60 units on a scale
Standard Deviation .74
3RP-AYA Acceptability: Five Questions
How convenient was the program
3.67 units on a scale
Standard Deviation .71
3RP-AYA Acceptability: Five Questions
How satisfied are you with the content?
3.6 units on a scale
Standard Deviation .62

Adverse Events

Waitlist Control

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

3RP Group Sessions

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Giselle K. Perez

Massachusetts General Hospital/Harvard Medical Schoool

Phone: 617-724-0765

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place