Cardiovascular Function in Acute Leukemia

NCT ID: NCT03760237

Last Updated: 2024-10-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

84 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-12-10

Study Completion Date

2024-05-06

Brief Summary

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An observational, prospective study to describe the rates and predictors of cardiovascular events in patients with acute leukemia.

Detailed Description

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Patients recently diagnosed with acute leukemia and who will initiating chemotherapy will be enrolled and followed serially with blood collection, echocardiogram, arterial applanation tonometry, and questionnaires for 1 year.

Conditions

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Leukemia, Myeloid, Acute Leukemia, Lymphoid, Acute Cardiotoxicity

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Acute Leukemia

Observation only. Patients newly diagnosed with acute leukemia who are scheduled to start treatment with chemotherapy will be enrolled and followed serially with blood collection, echocardiogram, arterial applanation tonometry, and questionnaires for 1 year.

observation only

Intervention Type OTHER

No intervention, observational study only

Interventions

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observation only

No intervention, observational study only

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Older than 18 years of age,
* New diagnosis of untreated acute leukemia (prior treatment for myelodysplastic syndrome or myeloproliferative neoplams or prior treatment with an anthracycline for breast cancer, Hodgkin's lymphoma, non-Hodgkin's lymphoma or another diagnosis will be included).
* Signed the informed consent form

Exclusion Criteria

• Unable to provide informed consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Abramson Cancer Center at Penn Medicine

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Marielle Scherrer-Crosbie, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Pennsylvania

Locations

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Abramson Cancer Center of the University of Pennsylvania

Philadelphia, Pennsylvania, United States

Site Status

Countries

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United States

Other Identifiers

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UPCC48418

Identifier Type: -

Identifier Source: org_study_id

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