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Isometric Hand Grip Training in Obstructive Sleep Apnea (OSA)

NCT ID: NCT03757169

Last Updated: 2018-11-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

18 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-12-17

Study Completion Date

2019-02-28

Brief Summary

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Obstructive sleep apnea (OSA) is a common clinical condition, involving the development of arterial hypertension. A Meta analysis study have shown that isometric hand grip training promotes blood pressure reduction. It is going to be conducted a clinical trail to determine the effects of hand grip training in OSA patients to change the arterial hypertension.

Detailed Description

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Background: obstructive sleep apnea (OSA) is a common clinical condition, involving the development of arterial hypertension. Meta analysis study have shown that isometric hand grip strength promotes blood pressure reduction, and its reduction is higher than that observed after aerobic training. Objective: to analyze the effects of the isometric hand grip on blood pressure changes of patients with uncontrolled arterial hypertension with OSA. Methods: a randomized controlled trial involving 18 adults with OSA and uncontrolled arterial hypertension of both sexes, randomized between control group (receive general guidelines) and hand grip group. 12 weeks of training with load equivalent to 30% of maximum voluntary capacity was performed. All participants will be submitted for evaluation of blood pressure (BP) central and brachial, pulse wave velocity, full polysomnography,before and after the study protocol (the change from the baseline at 12 weeks). Expected results: the authors believe that hand grip training can change (reduce) blood pressure in patient with OSA.

Conditions

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Obstructive Sleep Apnea Hypertension

Keywords

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training hand grip exercise

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

There are two randomized groups.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Control group

Verbal informations about the disease, and exercise behavior, and nutrition.

Group Type ACTIVE_COMPARATOR

Control

Intervention Type OTHER

The patients will receive verbal orientations about the OSA and the arterial hypertension.

Hand grip group

Three supervised sessions por week: 4 series (2 at each arm) of two minutes of isometric hand grip contraction at 30% of maximal voluntary contraction. Between series there will be two minutes to rest.

Group Type ACTIVE_COMPARATOR

Hand grip isometric contraction

Intervention Type OTHER

The patients at the Hand Grip group will perform 12 weeks of hand grip exercises, three times/week for 16 minutes with time to rest.

Interventions

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Hand grip isometric contraction

The patients at the Hand Grip group will perform 12 weeks of hand grip exercises, three times/week for 16 minutes with time to rest.

Intervention Type OTHER

Control

The patients will receive verbal orientations about the OSA and the arterial hypertension.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* OSA diagnose based on polysomnography,
* Apnea-Hypopnea Index (AHI) \> 5,
* arterial hypertension (systolic arterial pressure \> 140 mmHg or diastolic arterial pressure \> 90 mmHg)

Exclusion Criteria

* other heart disease
Minimum Eligible Age

30 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Pernambuco

OTHER

Sponsor Role lead

Responsible Party

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Rodrigo Pinto Pedrosa

Head of sleep laboratory and heart emergency room of Pernambuco , Principal Investigator.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Pronto Socorro Cardiológico de Pernambuco - Procape

Recife, Pernambuco, Brazil

Site Status RECRUITING

Countries

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Brazil

Central Contacts

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Flávio MD Andrade, Ms

Role: CONTACT

Phone: +55 81 99635 5417

Email: [email protected]

Facility Contacts

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Rodrigo Pedrosa, PhD

Role: primary

Flávio MD Andrade, Ms

Role: backup

Other Identifiers

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isopress03

Identifier Type: -

Identifier Source: org_study_id