Cell Surface Marker Expression in Autoimmune Diseases

NCT ID: NCT03757065

Last Updated: 2020-08-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

14 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-06-12

Study Completion Date

2019-10-25

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study is designed to explore the expression of cell-surface markers in the following seven disease areas: (a) systemic lupus erythematosus, (b) Sjogren's syndrome, (c) multiple sclerosis, (d) systemic sclerosis, (e) Crohn's disease, (f) ulcerative colitis and (g) inflammatory myositis.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Systemic Lupus Erythematosus Sjogren's Syndrome Multiple Sclerosis Systemic Sclerosis Crohn's Disease Ulcerative Colitis Inflammatory Myositis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Systemic Lupus Erythematosus

No interventions assigned to this group

Sjogren's Syndrome

No interventions assigned to this group

Multiple Sclerosis

No interventions assigned to this group

Systemic Sclerosis

No interventions assigned to this group

Crohn's Disease

No interventions assigned to this group

Ulcerative Colitis

No interventions assigned to this group

Inflammatory Myositis

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Male or female participants 19 years of age or older.
2. Participant or legal surrogate able and willing to provide written, informed consent.
3. Participant is, or has been undergoing care for one of the specified diseases in a participating centre with a confirmed clinical diagnosis of the specified disease.
4. Participant has or will provide the relevant peripheral blood (required) and normal practice tissue specimens (if available).
5. Participant has one of the following target auto-immune or inflammatory diseases diagnosed according to local clinical practice guidelines:

1. Crohn's Disease
2. Inflammatory myositis
3. Multiple sclerosis
4. Sjogren's syndrome
5. Systemic lupus erythematosus
6. Systemic sclerosis
7. Ulcerative colitis

Exclusion Criteria

1. Participants receiving investigational therapy within 30 days or 5 half-lives, whichever is longer, prior to enrolment.
2. Participants suffering from any additional disease that may interfere with the biomarker signals as per the investigator's discretion.
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Alpine Immune Sciences, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Jan Hillson, MD

Role: STUDY_DIRECTOR

Alpine Immune Sciences

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

GI Research Institute

Vancouver, British Columbia, Canada

Site Status

Mary Pack Arthritis Center

Vancouver, , Canada

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Canada

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

ALPN000-001

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

MRI for Screening and Monitoring Scleroderma ILD
NCT05204355 ACTIVE_NOT_RECRUITING
Longitudinal Innate Immunity and Aging Study
NCT03944603 ACTIVE_NOT_RECRUITING