Feasibility of Constraint-induced Therapy Combined With Visual-spatial Cueing Strategy in Patients With Acute Stroke

NCT ID: NCT03754166

Last Updated: 2020-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

8 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-01-18

Study Completion Date

2020-02-12

Brief Summary

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The aim of this study is to test the feasibility of a constraint intervention combined with visual-spatial cueing strategy in patients with acute stroke to improve their daily life activities.

Detailed Description

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As part of treatment in acute stroke (from D0 to D14), the investigators were able to observe that despite motor recovery during physiotherapy sessions, it remained difficult for some patients to use their affected arm (AA) during activities of daily life (ADL). This mechanism of "learned non-use" would be due to a cognitive process decreasing the use of the AA and could partly explain that 75% of patients maintain an upper limb deficit at 3-6 month post-stroke.

In order to combat this phenomenon, a bottom up method (sensorimotor action on the deficit) of constraint-induced movement therapy (CIMT) has been developed and consists in immobilizing the unaffected arm to force the use of the AA.

This technique has proved its effectiveness in the chronic phase and has also recently been proven to improve motor performance in the acute phase. Transposing progress on ADL, however, remains difficult because CIMT does not contain adequate behavioral strategies.

To help the patient mobilize these strategies, coupling of CIMT with a top-down method (conscious action on motor skills) has been successfully tested as an intervention of an occupational therapist with the patient at least 1h / day. This intervention remains not compatible with the investigators care organization because the caregiver can not spend that amount of time with each patient.

Investigators therefore propose to associate CIMT with another top down technique: visual-spatial cueing (use of panels and/or visual messages to encourage the conscious use of the AA) and investigators want to evaluate the effectiveness of this treatment on learning transfer to ADL.

The objective of our study will be to test the feasibility of setting up such an intervention.

Conditions

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Acute Stroke

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Constraint-induced movement therapy

Patient's unaffected arm is restrained, by a glove including thumb, during activities of daily life (bathing, grooming, dressing and feeding = approx. 4h/day).

Visual spatial cueing is displayed in the bedroom and the bathroom.

Group Type EXPERIMENTAL

Constraint-induced movement therapy

Intervention Type OTHER

Patient's unaffected arm is restrained, by a glove including thumb, during activities of daily life (bathing, grooming, dressing and feeding = approx. 4h/day).

Visual spatial cueing is displayed in the bedroom and the bathroom.

Usual care

Usual care of the neurovascular unit. = No constraint, no cueing, and same physiotherapy intervention as experimental arm.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Constraint-induced movement therapy

Patient's unaffected arm is restrained, by a glove including thumb, during activities of daily life (bathing, grooming, dressing and feeding = approx. 4h/day).

Visual spatial cueing is displayed in the bedroom and the bathroom.

Intervention Type OTHER

Other Intervention Names

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Visual-spatial cueing : top down

Eligibility Criteria

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Inclusion Criteria

* Hospitalized patient in neurovascular unit for stroke
* Time since stroke between 2 and 4 days
* Movement capacity of the upper arm (against gravity) :
* Ability to extend actively the metacarpophalangeal and interphalangeal joints at least 10°, and the wrist 20°
* Ability to bend actively the elbow at least 45°
* Ability to bend and abduct actively the shoulder at least ≥ 45°
* Age ≥ 18 years old
* Patient agreement to join the study
* Patient covered by french social security

Exclusion Criteria

* Excessive spasticity : score \> 2 on the modified Ashworth scale
* Excessive pain in the affected arm : score ≥ 4 on the visual analogue scale
* Joint limitation on the affected arm
* Patient under guardianship or curatorship
* Pregnant or breastfeeding woman
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Nantes University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ambre Komonski

Role: PRINCIPAL_INVESTIGATOR

Nantes University Hospital

Locations

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Service de Neurologie, CHU Nantes

Nantes, , France

Site Status

Countries

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France

Other Identifiers

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RC18_0288

Identifier Type: -

Identifier Source: org_study_id