The Effectiveness of Global Postural Reeducation on Alzheimer Disease Patients

NCT ID: NCT03732053

Last Updated: 2019-11-19

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 135 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2016-12-05
• Study Completion Date: 2017-07-03

Brief Summary

This research study is developed on an experimental design with randomized controlled intervention were participated 135 subjects with AD including 45 of the control group. It lasted 6 months with pre-post tests (T0-T1) executed before and after six months of treatment. By having in focus the evaluation of GPR therapy effects on cognitive, proprioceptive, depressive, autonomy, gait and life quality of the above mentioned subjects.

Detailed Description

In order to assess the cognitive abilities of the patients a cognitive test was administered which acts through a scale concerning depression and mood evaluation as well as a questionnaire was developed aiming to evaluate the examined subjects' functional abilities: Mini Mental State Examination (MMSE), Quality of Life in Alzheimer Disease (QoL-AD), geriatric Depression Scale (GDS), Barthel Index (BI), Neuropsychiatric Inventory (NPI), Tinetti Scale (TS).

Conditions

Alzheimer's Type Dementia; Cognitive Decline; Postural; Strain

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

GPR Intervention Research group

A total of 135 subjects with AD in the mild or moderate phase participated in the study from which 90 pertain to research group.The intervention implemented to the patients with AD was the Global Postural therapy which lasted about 30-40 min in repeated sessions of 2 meetings per week by making 48 sessions in total during a six month period.

Group Type: EXPERIMENTAL

GPR Intervention Research group

Intervention Type: OTHER

The research intervention consisted in the reappointment of three GPR therapeutic postures.

Control Group

45 subjects of the study belongs to the control group which has not received the same treatment .

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

GPR Intervention Research group

The research intervention consisted in the reappointment of three GPR therapeutic postures.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Clinical diagnosis of Alzheimer's Disease
• Older than 40 years of age
• Male and female
• Intellectual disability
• Cognitive impairment
• Able to do daily activities on his own
• No presence of any other neurological and psychological disease
• No presence of brain tumors

Exclusion Criteria

• No presence of Alzheimer's Disease
• Under 40 years old
• Presence of brain tumors
• Neurological patients
• Presence of psychiatric disease
• Depression symptoms
• Presence of neuromuscular disease
• Ictus
• Aggressive patients

• Minimum Eligible Age: 40 Years
• Maximum Eligible Age: 95 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Universidad Católica San Antonio de Murcia

OTHER

Sponsor Role: lead

Responsible Party

Jasemin Todri

PhD Candidate in Health Science

Responsibility Role: PRINCIPAL_INVESTIGATOR

References

Todri J, Lena O, Todri A, Fuentes JM. Does the Global Postural Re-Education Affect the Psychological and Postural Aspects of Alzheimer Disease Patients? A Six Months Quasi-Experimental Study. Curr Alzheimer Res. 2021;18(13):1057-1065. doi: 10.2174/1567205019666211223094811.

Reference Type: DERIVED

PMID: 34951386 (View on PubMed)

Other Identifiers

BJ8674287

Identifier Type: -

Identifier Source: org_study_id