Everolimus Related Pneumonitis in MBC

NCT ID: NCT03730428

Last Updated: 2020-08-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

86 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-07-15

Study Completion Date

2020-06-15

Brief Summary

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To study the drug-related pneumonitis during mTOR inhibitor therapy in patients with metastatic breast cancer.

Detailed Description

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Conditions

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Everolimus Pneumonitis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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pneumonitis group

Patients who developed drug-related pneumonitis after treated with everolims

No interventions assigned to this group

non-pneumonitis group

Patients who didn't develop drug-related pneumonitis after treated with everolims

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Postmenopausal woman (or premenopausal women treated with LHRHa) diagnosed with HR+,HER2- metastatic breast cancer
2. Treated with everolimus for at least one month in metastatic setting
3. With baseline and at least one follow-up chest CT during everolimus therapy.
4. Complete medical history

Exclusion Criteria

1. Incomplete medical history
2. Radiographic imaging unavailable
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fudan University

OTHER

Sponsor Role lead

Responsible Party

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Biyun Wang, MD

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Biyun Wang, Professor

Role: PRINCIPAL_INVESTIGATOR

Fudan University

Locations

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Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, China

Site Status

Countries

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China

Other Identifiers

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YOUNGBC-5

Identifier Type: -

Identifier Source: org_study_id

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