Trial Outcomes & Findings for Exploratory Study to Evaluate Uncorrected Distance Vision and Quality of Vision After Light Treatments of an Implanted RxSight Light Adjustable Lens (RXLAL) With The Light Delivery Device (LDD) in Subjects With Preoperative Corneal Astigmatism (NCT NCT03729024)

NCT ID: NCT03729024

Last Updated: 2021-08-06

Results Overview

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

21 participants

Primary outcome timeframe

6 months

Results posted on

2021-08-06

Participant Flow

Unit of analysis: Eyes

Participant milestones

Participant milestones
Measure
Light Adjustable Lens (LAL) and Light Delivery Device (LDD)
Light Adjustable lens (LAL) and Light Delivery Device (LDD): Primary and Fellow eyes will receive Light adjustable lens with Light delivery Device treatments
Overall Study
STARTED
21 42
Overall Study
COMPLETED
21 42
Overall Study
NOT COMPLETED
0 0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Exploratory Study to Evaluate Uncorrected Distance Vision and Quality of Vision After Light Treatments of an Implanted RxSight Light Adjustable Lens (RXLAL) With The Light Delivery Device (LDD) in Subjects With Preoperative Corneal Astigmatism

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Light Adjustable Lens (LAL) and Light Delivery Device (LDD)
n=42 Eyes
Light Adjustable lens (LAL) and Light Delivery Device (LDD): Primary and Fellow eyes will receive Light adjustable lens with Light delivery Device treatments
Age, Continuous
68.3 years
STANDARD_DEVIATION 5.3 • n=5 Participants
Sex: Female, Male
Female
12 Participants
n=5 Participants
Sex: Female, Male
Male
9 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
18 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
3 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Region of Enrollment
Mexico
21 participants
n=5 Participants

PRIMARY outcome

Timeframe: 6 months

Outcome measures

Outcome measures
Measure
Light Adjustable Lens (LAL) and Light Delivery Device (LDD)
n=42 Eyes
Light Adjustable lens (LAL) and Light Delivery Device (LDD): Primary and Fellow eyes will receive Light adjustable lens with Light delivery Device treatments
Percent of Eyes With UCDVA of 20/20 or Better
41 Eyes

Adverse Events

Light Adjustable Lens (LAL) and Light Delivery Device (LDD)

Serious events: 0 serious events
Other events: 1 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
Light Adjustable Lens (LAL) and Light Delivery Device (LDD)
n=42 participants at risk
Light Adjustable lens (LAL) and Light Delivery Device (LDD): Primary and Fellow eyes will receive Light adjustable lens with Light delivery Device treatments
Eye disorders
Cystoid Macular Edema
2.4%
1/42 • Number of events 1 • Through study completion, an average of 6 months
The at Risk number in All-Cause Mortality represent whole participants while the at Risk number in the Serious and Other (Not Including Serious) Adverse Events tables represent the number of eyes. Non-ocular adverse events were not collected.

Additional Information

Jeffrey Ha, Senior Director of Clinical Research

RxSight

Phone: 949-521-7870

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place