NIDEK Gonioscope GS-1 for Glaucoma

NCT ID: NCT03715231

Last Updated: 2021-12-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-06-12

Study Completion Date

2021-05-26

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The Gonioscope GS-1 is an ophthalmic camera with gonioscopic prism that is intended to capture, display and store images of the anterior chamber angle and its peripheral part. This study evaluates the efficiency of Gonioscope GS-1 in glaucoma patients.With the captured images, the glaucoma diagnosis and post-operative observation are enabled.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Glaucoma

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Glaucoma & Glaucoma Suspect Patients

Patients with Glaucomatous optic neuropathy

Group Type EXPERIMENTAL

NIDEK Gonioscope GS-1

Intervention Type OTHER

To determine inter-observer repeatability when using this device, two observers will examine each image obtained from NIDEK Gonioscope GS-1 and separately determine the iridocorneal angle. Inter-observer repeatability will be tested using Pearson correlation.

Standard Digital Gonioscopic Images

Intervention Type OTHER

To determine inter-observer repeatability when using this device, two observers will examine each image obtained from NIDEK Gonioscope GS-1 and separately determine the iridocorneal angle. Inter-observer repeatability will be tested using Pearson correlation.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

NIDEK Gonioscope GS-1

To determine inter-observer repeatability when using this device, two observers will examine each image obtained from NIDEK Gonioscope GS-1 and separately determine the iridocorneal angle. Inter-observer repeatability will be tested using Pearson correlation.

Intervention Type OTHER

Standard Digital Gonioscopic Images

To determine inter-observer repeatability when using this device, two observers will examine each image obtained from NIDEK Gonioscope GS-1 and separately determine the iridocorneal angle. Inter-observer repeatability will be tested using Pearson correlation.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Diagnosed with glaucoma or glaucoma suspect

Glaucoma Suspect

* Glaucomatous optic neuropathy as described in the glaucoma patients below
* AND/OR ocular hypertension (IOP \> 21 mm Hg)
* Normal visual field

Glaucoma Patients

* Clinical characteristics of glaucoma: ONH abnormalities: global rim thinning, rim notch, or disc hemorrhage; RNFL defect
* Typical glaucomatous field loss in reliable VF, reproducible glaucoma hemifield tests labeled outside normal limits on at least two consecutive tests.
* Both eyes will be included, except in cases where only one eye meets study criteria

Exclusion Criteria

* Corneal opacities (scars, edema, etc.)
* Pregnant or planning to become pregnant
* Inability to fixate gaze
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

NYU Langone Health

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Joel Schuman

Role: PRINCIPAL_INVESTIGATOR

NYUMC Langone

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

NYU Langone Health

New York, New York, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

References

Explore related publications, articles, or registry entries linked to this study.

Madu CT, Phelps T, Schuman JS, Zambrano R, Lee TF, Panarelli J, Al-Aswad L, Wollstein G. Automated 360-degree goniophotography with the NIDEK Gonioscope GS-1 for glaucoma. PLoS One. 2023 Mar 7;18(3):e0270941. doi: 10.1371/journal.pone.0270941. eCollection 2023.

Reference Type DERIVED
PMID: 36881575 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

18-00429

Identifier Type: -

Identifier Source: org_study_id