Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
24 participants
INTERVENTIONAL
2018-10-24
2020-02-26
Brief Summary
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Detailed Description
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Therefore, this study aims to better regulate the response of the brain to rTMS. The findings of this study will provide the basis for future development of optimal rTMS treatment protocols for patients with swallowing difficulties.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
DOUBLE
Study Groups
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Sham 1Hz rTMS--5Hz rTMS
Participants will receive sham 1Hz rTMS, then immediately followed by 5Hz rTMS.
rTMS
rTMS is a non-invasive brain stimulation technique. It can regulate brain activities with electrical pulses sent to the brain through electromagnetic induction.
1Hz rTMS--5Hz rTMS
Participants will receive 1Hz rTMS, then immediately followed by 5Hz rTMS.
rTMS
rTMS is a non-invasive brain stimulation technique. It can regulate brain activities with electrical pulses sent to the brain through electromagnetic induction.
1Hz rTMS--30-minute break--5Hz rTMS
Participants will receive 1Hz rTMS, then followed by 30 minutes break, then followed by 5Hz rTMS.
rTMS
rTMS is a non-invasive brain stimulation technique. It can regulate brain activities with electrical pulses sent to the brain through electromagnetic induction.
1Hz rTMS--60-minute break--5Hz rTMS
Participants will receive 1Hz rTMS, then followed by 60 minutes break, then followed by 5Hz rTMS.
rTMS
rTMS is a non-invasive brain stimulation technique. It can regulate brain activities with electrical pulses sent to the brain through electromagnetic induction.
Sham 5Hz rTMS--1Hz rTMS
Participants will receive sham 5Hz rTMS, then immediately followed by 1Hz rTMS.
rTMS
rTMS is a non-invasive brain stimulation technique. It can regulate brain activities with electrical pulses sent to the brain through electromagnetic induction.
5Hz rTMS--1Hz rTMS
Participants will receive 5Hz rTMS, then immediately followed by 1Hz rTMS.
rTMS
rTMS is a non-invasive brain stimulation technique. It can regulate brain activities with electrical pulses sent to the brain through electromagnetic induction.
5Hz rTMS--45-minute break--1Hz rTMS
Participants will receive 5Hz rTMS, then followed by 45 minutes break, then followed by 1Hz rTMS.
rTMS
rTMS is a non-invasive brain stimulation technique. It can regulate brain activities with electrical pulses sent to the brain through electromagnetic induction.
5Hz rTMS--90-minute break--1Hz rTMS
Participants will receive 5Hz rTMS, then followed by 90 minutes break, then followed by 1Hz rTMS.
rTMS
rTMS is a non-invasive brain stimulation technique. It can regulate brain activities with electrical pulses sent to the brain through electromagnetic induction.
Interventions
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rTMS
rTMS is a non-invasive brain stimulation technique. It can regulate brain activities with electrical pulses sent to the brain through electromagnetic induction.
Eligibility Criteria
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Inclusion Criteria
* No medical complications or significant past medical history
Exclusion Criteria
* Previous history of neurosurgery;
* Previous swallowing problem;
* Implanted brain electrodes, cardiac pacemaker; or
* Use of medications (predominantly taking multiple anti-depressants) that lower neural threshold
18 Years
ALL
Yes
Sponsors
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University of Manchester
OTHER
Responsible Party
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Prof Shaheen Hamdy PhD FRCP
Professor of Neurogastroenterology
Principal Investigators
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Shaheen Hamdy, PhD, FRCP
Role: PRINCIPAL_INVESTIGATOR
The University of Manchester
Locations
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Salford Royal Foundation Trust
Salford, Greater Manchester, United Kingdom
Countries
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Other Identifiers
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2018-4900-7208
Identifier Type: -
Identifier Source: org_study_id