Virtual Reality for Symptoms Control in Palliative Care

NCT ID: NCT03698526

Last Updated: 2018-10-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

180 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-09-01

Study Completion Date

2019-12-15

Brief Summary

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The aim of this study is to evaluate how Virtual Reality (VR) can be used to control symptoms and improve the quality of life in palliative care. The interventional prospective case control study is planned to contain five phases including two control groups. The following describes only phase one to three.

In the pilot phase patients get a one-time application of the VR-Technology. After that, two control groups will be recruited from patients with 1. mamma carcinoma and the indication of (neo-) adjuvant radiotherapy and 2. before a colonoscopy-treatment. Both groups receive the VR application before treatment (radiotherapy/colonoscopy).

This first part proofs the application of Virtual Reality on patients in palliative care with the aim to control symptoms and reduce pain and anxiety.

The clinical study hypothesis bases on the assumption that VR reduces pain and anxiety and may have a positive influence on their quality of life.

Detailed Description

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Pilot phase:

After the enrolment and consent of participation the patient receives a questionnaire consisting of different independent assessments. The visual analogue scale with values from 1 to 10 quantifies subjective pain. A functional pain questionnaire (Pain-Out) is developed to assess the pain in between the last seven days, the associated limitations, the actions and side effects of combined pain therapy.

To measure the generic health-related quality of life the patient is asked to answer the EuroQoL Group 5-Dimension 5-Level Self Report Questionnaire (EQ-5D-5L).

A Virtual Reality application is offered immediately after the questionnaire has been completed. Following the application of VR the patient will receive VAS and functional pain questionnaires again to assess the change from baseline.

Control phase:

The following control phase is to review the effectiveness of VR application on the basis of two different control groups. In a randomized setting 30 patients with mamma carcinoma receive an application of VR before their radiotherapy. The second control group consists of 40 patients with an individual indication of a colonoscopy.

Instead of pain by VAS and QoL in the pilot phase each patient receives now the Hospital Anxiety and Depression Scale (HADS) before and after the application. The Functional Pain Questionnaire remains with the control group of patients with mamma carcinoma.

Conditions

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Palliative Care Virtual Reality Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SEQUENTIAL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Palliative care I

Palliative care

Group Type ACTIVE_COMPARATOR

Samsung Gear VR, Galaxy S8, Applied VR App

Intervention Type DEVICE

Virtual Reality Experience

Control II

Patients with mamma carcinoma and (neo-) adjuvant radiotherapy

Group Type ACTIVE_COMPARATOR

Samsung Gear VR, Galaxy S8, Applied VR App

Intervention Type DEVICE

Virtual Reality Experience

Control III

Patients before colonoscopy

Group Type ACTIVE_COMPARATOR

Samsung Gear VR, Galaxy S8, Applied VR App

Intervention Type DEVICE

Virtual Reality Experience

Interventions

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Samsung Gear VR, Galaxy S8, Applied VR App

Virtual Reality Experience

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Minimum age of 18 years
* Patient understands information for participation
* Patients are able to give informed written consent
* (Informed written) consent prior inclusion in study
* study arm I: Indication for palliative care due to any advanced life-limiting and progressive diseases
* control II: Patients with mamma carcinoma and (neo-) adjuvant radiotherapy
* control III: Patients before colonoscopy

Exclusion Criteria

* Epileptic seizures in medical history
* Patients with claustrophobia
* Patients with tendency to vertigo and motion sickness
* Age under 18 years
* No informed written consent
* Inability to understand information for participation, language difficulties (foreign nationals), hardness of hearing
* Blindness
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Palliativnetz Muenster gGmbH

UNKNOWN

Sponsor Role collaborator

University Hospital Muenster

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Philipp Lenz, MD

Role: PRINCIPAL_INVESTIGATOR

Institut of Palliative Care, University Hospital of Muenster

Locations

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Palliativnetz Muenster gGmbH

Münster, North Rhine-Westphalia, Germany

Site Status NOT_YET_RECRUITING

University Hospital Muenster

Münster, , Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Philipp Lenz, MD

Role: CONTACT

+4915254957580

Renate Schmidt, MD

Role: CONTACT

+492518346135

Facility Contacts

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Dr. med. Ulrike Hofmeister, MD

Role: primary

+49 (0)251 1625662

PD Dr. me.d Philipp Lenz, MD

Role: primary

0049/152/54957580

References

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Teunissen SC, Wesker W, Kruitwagen C, de Haes HC, Voest EE, de Graeff A. Symptom prevalence in patients with incurable cancer: a systematic review. J Pain Symptom Manage. 2007 Jul;34(1):94-104. doi: 10.1016/j.jpainsymman.2006.10.015. Epub 2007 May 23.

Reference Type BACKGROUND
PMID: 17509812 (View on PubMed)

Gold JI, Mahrer NE. Is Virtual Reality Ready for Prime Time in the Medical Space? A Randomized Control Trial of Pediatric Virtual Reality for Acute Procedural Pain Management. J Pediatr Psychol. 2018 Apr 1;43(3):266-275. doi: 10.1093/jpepsy/jsx129.

Reference Type BACKGROUND
PMID: 29053848 (View on PubMed)

Mosadeghi S, Reid MW, Martinez B, Rosen BT, Spiegel BM. Feasibility of an Immersive Virtual Reality Intervention for Hospitalized Patients: An Observational Cohort Study. JMIR Ment Health. 2016 Jun 27;3(2):e28. doi: 10.2196/mental.5801.

Reference Type BACKGROUND
PMID: 27349654 (View on PubMed)

Mahrer NE, Gold JI. The use of virtual reality for pain control: a review. Curr Pain Headache Rep. 2009 Apr;13(2):100-9. doi: 10.1007/s11916-009-0019-8.

Reference Type BACKGROUND
PMID: 19272275 (View on PubMed)

Hoffman HG, Patterson DR, Carrougher GJ, Sharar SR. Effectiveness of virtual reality-based pain control with multiple treatments. Clin J Pain. 2001 Sep;17(3):229-35. doi: 10.1097/00002508-200109000-00007.

Reference Type BACKGROUND
PMID: 11587113 (View on PubMed)

Other Identifiers

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VRPC2018

Identifier Type: -

Identifier Source: org_study_id

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