Low Level Laser in Isolated Cleft Palate Repair Versus Surgical Correction Without LLL in Healing Process

NCT ID: NCT03688737

Last Updated: 2018-09-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-10-31

Study Completion Date

2020-12-31

Brief Summary

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Does the use of low level laser (LLL) after surgical correction of cleft palate improve healing and decrease incidence of oronasal fistula?

Detailed Description

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Primary objective:

To evaluate the effect of adjunctive use of LLL after surgical correction of cleft palate in improving healing among children with cleft palate Secondary objectives To evaluate the effect of adjunctive use of LLL after surgical correction of cleft palate in decreasing incidence of oronasal fistula after surgical repair among children with cleft palate Study group: Will use LLL after surgical correction of cleft palate at day of surgery, 1st day and 3rd day Control group: Surgical correction of cleft palate without Adjunctive use of LLL

Inclusion criteria:

1. Age: between 6 to 18 months of age
2. Patient has isolated cleft palate

Exclusion criteria:

1. Systemic disease
2. Hematological disorder Outcome: Outcome measure (s) (1ry, 2ry) 1ry: healing assessment 2ry: occurrence of oronasal fistula

Conditions

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Cleft Palate Children Laser

Keywords

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low level laser , cleft palate , healing

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Participants will be randomly assigned to either control or study group in the ratio of 1:1 using random number table.
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
Single blinded study. Blinding to the patient will be ensured by masking the instruments during the follow up. The patient will be informed of the steps of the follow up (as mentioned in the consent form) without getting into details of the method of follow up.

Study Groups

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control group

A) Control group:

Has Surgical procedures "von Langenbeck technique " to repair cleft palate and will come for follow up visit at day of surgery, 1st day and 3rd day for placebo device like LLL and come for follow up visits at 5th day ,2 weeks, month and 3 months postoperative

Group Type PLACEBO_COMPARATOR

placebo

Intervention Type OTHER

placebo like device as it like low level laser device shape but with no effect to blind the intervention

study group

B) Study group:

This group will be subjected to the same surgical procedure "von Langenbeck technique "to repair cleft palate but low level laser Therapy will be at day of surgery, 1st day and 3rd day and come for follow up visits at 5th day ,2 weeks, month and 3 months postoperative

Group Type ACTIVE_COMPARATOR

low level laser

Intervention Type OTHER

LLLT with wavelength (λ) of (600 nm to 700nm), The laser will be held 1 cm away from the surface of the target tissue, the irradiated area is 0,5 cm2.The area of impact is the surgical wound zone and the neighboring 0,5-1,0 cm of the adjacent oral mucosa for 1min and 22sec, at day of surgery, 1st day and 3rd day and come for follow up visits at 5th day ,2 weeks, month and 3 months postoperative

Interventions

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low level laser

LLLT with wavelength (λ) of (600 nm to 700nm), The laser will be held 1 cm away from the surface of the target tissue, the irradiated area is 0,5 cm2.The area of impact is the surgical wound zone and the neighboring 0,5-1,0 cm of the adjacent oral mucosa for 1min and 22sec, at day of surgery, 1st day and 3rd day and come for follow up visits at 5th day ,2 weeks, month and 3 months postoperative

Intervention Type OTHER

placebo

placebo like device as it like low level laser device shape but with no effect to blind the intervention

Intervention Type OTHER

Other Intervention Names

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wavelength (λ) of (600 nm to 700nm)

Eligibility Criteria

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Inclusion Criteria

1. Age: between 6 to 18 months of age
2. Patient has isolated cleft palate

Exclusion Criteria

1. Systemic disease
2. Hematological disorder
Minimum Eligible Age

6 Months

Maximum Eligible Age

18 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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El noman Mohamed Kamal El shafie

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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El noman MK El shafie, M.Sc.

Role: CONTACT

Phone: 002001063999203

Email: [email protected]

Basma GM Moussa, Prof

Role: CONTACT

Phone: 002001005644098

Other Identifiers

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172162009

Identifier Type: -

Identifier Source: org_study_id