Association Between Renal and Right Cardiac Functions After Urinary Sodium Depletion Following Cardiac Surgery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-06-01

Study Completion Date

2024-06-01

Brief Summary

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Following cardiac surgery, right ventricular function may be altered leading to increase central venous pressure and decrease in renal blood flow. The investigator's standard care includes use of diuretic to avoid interstitial fluid accumulation. The aim of the study is to assess cardiac and renal function before and after depletion by using diuretics

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Detailed Description

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The study will compare cardiac and renal data before and 6 hours after use of diuretic

* Echocardiographic measure of right function (S wave, TAPSE, ventricle surfaces, inferior vena cava diameter) and left function (LVEF, cardiac output
* Renal function: cumulative diuresis, creatinine level variation and incidence of acute kidney injury using KDIGO classification (creatinine level\>26.5 or diuresis\<0.05 ml kg-1 h-1)

Conditions

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Cardiorenal Syndrome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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diuretic use

use of diuretic

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

patient undergoing elective cardiac surgery under cardiopulmonary bypass

Exclusion Criteria

* heart transplantation
* use of vasopressor
* chronic renal disease (DGF under 30 ml min-1)
* endocarditis
* patient under ECLS or CPIA
* patient under 18-year-old

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No