A Mediterranean Diet Nutrition Education Program for the Reduction of Cardiovascular Disease Risk in the Southeastern U.S.

NCT ID: NCT03683134

Last Updated: 2018-09-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

58 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-01-23

Study Completion Date

2017-09-07

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

A 12-week, randomized nutrition intervention for the reduction of cardiovascular disease risk factors in a high-risk population in the southeastern United States. The primary objective of this pilot study was to assess the efficacy of a Mediterranean diet intervention (education + extra-virgin olive oil (EVOO) and mixed nut supplementation) versus that of an American Heart Association (AHA) nutrition intervention (education) on serum blood lipid levels as markers for cardiovascular disease risk. Researchers conducting this trial hypothesize that a greater reduction will be seen in cardiovascular disease risk factors in the Mediterranean diet intervention.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cardiovascular Diseases Cardiovascular Risk Factor Obesity

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Caregivers Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Mediterranean diet group

Participants will receive both nutrition education on patterns of a Mediterranean style diet as well as olive oil and mixed nuts.

Group Type EXPERIMENTAL

Mediterranean diet

Intervention Type BEHAVIORAL

Participants will receive nutrition education and educational materials from a registered dietitian on patients on the patterns of a Mediterranean style diet. Seven education sessions will be delivered through an online platform. Participants will be asked to complete one education session per week for the first six weeks and the final session at week 9.

Olive oil and mixed nuts

Intervention Type DIETARY_SUPPLEMENT

Participants in the Mediterranean diet group will receive 3 liters of extra-virgin olive oil and 3 pounds of mixed nuts (1.5 pounds raw almonds and 1.5 pounds raw walnuts) at baseline and at 6 weeks. Participants will be educated by oral and written means, on consumption goals of the nuts and olive oil.

American Heart Association group

Participants will receive nutrition education on the dietary recommendations for heart health from the American Heart Association.

Group Type ACTIVE_COMPARATOR

American Heart Association

Intervention Type BEHAVIORAL

Participants will receive nutrition education and educational materials from a registered dietitian on patients on the dietary recommendations from the American Heart Association for heart health. Seven education sessions will be delivered through an online platform. Participants will be asked to complete one education session per week for the first six weeks and the final session at week 9.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Mediterranean diet

Participants will receive nutrition education and educational materials from a registered dietitian on patients on the patterns of a Mediterranean style diet. Seven education sessions will be delivered through an online platform. Participants will be asked to complete one education session per week for the first six weeks and the final session at week 9.

Intervention Type BEHAVIORAL

Olive oil and mixed nuts

Participants in the Mediterranean diet group will receive 3 liters of extra-virgin olive oil and 3 pounds of mixed nuts (1.5 pounds raw almonds and 1.5 pounds raw walnuts) at baseline and at 6 weeks. Participants will be educated by oral and written means, on consumption goals of the nuts and olive oil.

Intervention Type DIETARY_SUPPLEMENT

American Heart Association

Participants will receive nutrition education and educational materials from a registered dietitian on patients on the dietary recommendations from the American Heart Association for heart health. Seven education sessions will be delivered through an online platform. Participants will be asked to complete one education session per week for the first six weeks and the final session at week 9.

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Enrolled in Auburn University's health insurance program during the course of the study or a dependent of the enrollee during the course of the study
* BMI \>24.9 (kg/m2)
* AND Meets two or more of the following
* Screening values classified in the "yellow" or "red" zone for:
* Systolic blood pressure (mmHg): Yellow zone: ≥140, Red zone: ≥160;
* Diastolic Blood pressure (mmHg): Yellow zone: ≥90, Red zone: ≥ 100;
* Fasting blood glucose (mm/dL): Yellow zone: ≥100, Red zone: ≥ 126
* Blood glucose (random) (mg/dL): Yellow zone: 140-200, Red zone \> 200
* Total Cholesterol (mg/dL): Yellow zone: ≥200, red zone: ≥250
* Have a pre-existing diagnosis of hypertension, pre-diabetes, or hypercholesterolemia
* Current smoker (≥1 cigarette/day)
* Are: male (age: 55-80) or female (age: 60-80)
* A family history of premature coronary heart disease
* High risk ethnicity: Black, African American, American Indians/Alaska Natives, Non-Hispanic blacks, Mexican-Americans, Asian, Hispanic/Latino

Exclusion Criteria

* Minors that are less than 19 years of age
* Individuals who are not enrolled in the Auburn University health insurance program for the 2016 plan year at baseline and have not yet completed initial visit
* Individuals who have not completed their 2015 "Healthy Tigers" biometric screening between January 1st and December 31st, 2015 (these can be completed by the "Healthy Tigers" staff or by submitting a healthcare provider form from the individuals' physician to the "Healthy Tigers" office), unless enrolled in "TigerMeds".
* Individuals who are pregnant or who intend to become pregnant during the 12-week health and wellness challenge.
* Individuals who anticipate absence or travel throughout the study that would interfere with their ability to complete the analysis at the mid-point and end of challenge.
* Patients with a peanut, tree nut, or olive oil food allergy or intolerance.
* Patients who are unable or unwilling to travel to Auburn University main campus for live health and wellness challenge events, individual assessments, personal appointments, and pre- and post- data collection
* Individuals who have NOT been stabilized on medication to treat or manage high blood pressure, high cholesterol, dyslipidemia, or pre diabetes for at least 12 weeks prior to the study.
* Patients who do not have access to the internet and therefore unable to complete the education portion of the study
* Individuals who have a pacemaker
* Patients who decline participation during informed consent
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Auburn University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Michael W. Greene

Director, Auburn University Metabolic Phenotyping Laboratory

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Michael W Greene, PhD

Role: STUDY_CHAIR

Auburn University

Amy W Willis, MS, RD

Role: PRINCIPAL_INVESTIGATOR

Auburn University

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Auburn University Pharmaceutical Care Center

Auburn, Alabama, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Provided Documents

Download supplemental materials such as informed consent forms, study protocols, or participant manuals.

Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

The Healthy Hearts Program

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Primary Prevention Program
NCT03927196 COMPLETED NA
Exercise Training in Older Diabetic Women
NCT00341614 COMPLETED PHASE1
Nutrition Education
NCT00005728 COMPLETED
Lifestyle Heart Trial
NCT00000471 COMPLETED PHASE2
CVD Risk Reduction Trial
NCT00473785 COMPLETED NA