Diagnosis and Intervention of Complicated Twin Diseases

NCT ID: NCT03650985

Last Updated: 2018-09-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-08-31

Study Completion Date

2022-08-31

Brief Summary

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Fetal medicine in China is still a new, young discipline, and the development is very rapid. After nearly 10 years of development, the clinical diagnosis and treatment guidelines of some complicated twin diseases has been established , but they are still needed to be improved. Through this study, the investigators expect to achieve better prediction indicators and early intrauterine precise diagnosis of complicated twin diseases. Also, better procedures of implementing effective intrauterine intervention and assessing the safety and effectiveness of intrauterine intervention are anticipated to be established.

Detailed Description

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A better guideline for complicated twin diseases are anticipated to be established in China. Molecular genetics and imaging technology are applied to evaluate the outcome and prognosis of intrauterine intervention for complex twin diseases. 3D printing technology is used to assist the preoperative evaluation of fetal intrauterine intervention. Better fetal intrauterine intervention technique and prognosis evaluation are expected to be established.

Conditions

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Twin Diseases

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Pregnancy women with complicated twin diseases, who are able to withstand risks of intrauterine treatments and informed consent.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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TOCTD

Pregnancy women with complicated twin diseases, who are able to withstand risks of intrauterine treatments and informed consent, will be involved. Fetoscope technique will be administered in suitable patients.

Group Type EXPERIMENTAL

Fetoscope technique

Intervention Type PROCEDURE

Intrauterine intervention with fetoscope technique will be applied to treat complex twin diseases with intention to improve the prognosis of patients.

Interventions

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Fetoscope technique

Intrauterine intervention with fetoscope technique will be applied to treat complex twin diseases with intention to improve the prognosis of patients.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Pregnancy women with complicated twin diseases who are able to withstand intrauterine treatment and consent informed.

Exclusion Criteria

* Pregnancy women who refuse intrauterine treatment.
Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Shengjing Hospital

OTHER

Sponsor Role lead

Responsible Party

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Caixia Liu

Director of the second obstetrical department

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Caixia Liu

Role: PRINCIPAL_INVESTIGATOR

Shengjing Hospital

Locations

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Shengjing Hospital

Shenyang, Liaoning, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Caixia Liu

Role: CONTACT

86-18902451716

Shaojiang Liu

Role: CONTACT

86-18002454803

Facility Contacts

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Shaowei Yin, PhD

Role: primary

86-18902458403

Shaojiang Liu

Role: backup

86-18002454803

Other Identifiers

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DICTD

Identifier Type: -

Identifier Source: org_study_id

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