Anti-VEGF Instead of Intraoperative Fan-shaped Photocoagulation in BRVO Combined With Vitreous Hemorrhage

NCT ID: NCT03637283

Last Updated: 2018-08-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-10-01

Study Completion Date

2021-12-01

Brief Summary

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To evaluate the efficacy and safety of Anti-VEGF instead of intraoperative fan-shaped photocoagulation in BRVO combined with vitreous hemorrhage.

Detailed Description

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Conditions

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Anti-VEGF Branch Retinal Vein Occlusion Vitrectomy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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anti-VEGF

vitreoretinal surgery combined with intraoperative anti-VEGF

Group Type EXPERIMENTAL

anti-VEGF

Intervention Type PROCEDURE

vitreoretinal surgery combined with intraoperative anti-VEGF

fan-shaped photocoagulation

vitreoretinal surgery combined with fan-shaped photocoagulation

Group Type ACTIVE_COMPARATOR

fan-shaped photocoagulation

Intervention Type PROCEDURE

vitreoretinal surgery combined with intraoperative fan-shaped photocoagulation

Interventions

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anti-VEGF

vitreoretinal surgery combined with intraoperative anti-VEGF

Intervention Type PROCEDURE

fan-shaped photocoagulation

vitreoretinal surgery combined with intraoperative fan-shaped photocoagulation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. Age ≥ 18 years old;
2. BRVO is diagnosed
3. Vitreous hemorrhage
4. Vitreous hemorrhage combined with mild retinal fibrovascular proliferation (early fibrous vascular membrane, thin fibrous vascular membrane, loose retinal adhesion and intact local retinal structure)

Exclusion Criteria

1. BRVO combined with severe retinal fibrovascular proliferation (long-term fibrovascular membrane, thick fibrous vascular membrane and tightly attached to the retina, deformation of local retinal, retinal tear or suspension of retinal vein )
2. BRVO combined with retinal detachment
3. Retinal veins are completely whitened
4. iris neovascularization or neovascular glaucoma
5. Combined glaucoma
6. combined with other retinopathy
7. Received anti-VEGF treatment within 3 months before surgery
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wenzhou Medical University

OTHER

Sponsor Role lead

Responsible Party

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Xiangtian Zhou

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Yong Wei, M.D

Role: PRINCIPAL_INVESTIGATOR

The Eye Hospital of Wenzhou Medical University

Central Contacts

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Yong Wei, M.D

Role: CONTACT

+86 15057551266

Wei Lin, M.D

Role: CONTACT

+86 13587560390

Other Identifiers

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10008

Identifier Type: -

Identifier Source: org_study_id

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