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Effect of Kefir on Appetite

NCT ID: NCT03636217

Last Updated: 2020-11-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-11-15

Study Completion Date

2017-05-31

Brief Summary

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This study aimed to determine the effect of kefir on appetite in healthy subjects. A randomized, single-blind, and 3-intervention crossover trial included 22 healthy and normal-weight (BMI 18.5-25 kg/m2) females aged 21-24 years. Participants were recruited to three test meals: an LGI-Milk, an LGI-Kefir, and an HGI-Kefir, with a one-week washout period. Appetite ratings were measured at 0, 15, 30, 60, 90, 120, 150, and 180 minutes. At the end of three hours, participants were served an ad libitum lunch meal. Then, the foods eaten at lunch were recorded and their energy and nutrient analysis was calculated.

Detailed Description

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Conditions

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Appetitive Behavior

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

SCREENING

Blinding Strategy

SINGLE

Participants

Study Groups

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LGI-Milk Breakfast

Low glycemic index and milk content (LGI-Milk) breakfast as a test meal

Group Type EXPERIMENTAL

LGI-Milk Breakfast

Intervention Type OTHER

This test meal with low glycemic index and milk were served as a breakfast after 12-hours fasting and participants were asked to consume the meal in full, within 15 min.

LGI-Kefir Breakfast

Low glycemic index and kefir content (LGI-Kefir) breakfast as a test meal

Group Type EXPERIMENTAL

LGI-Kefir Breakfast

Intervention Type OTHER

In crossover design, this test meal with low glycemic index and kefir was served as a breakfast to compare the LGI-Milk Breakfast.

HGI-Kefir Breakfast

High glycemic index and kefir content (HGI-Kefir) breakfast as a test meal

Group Type EXPERIMENTAL

HGI-Kefir Breakfast

Intervention Type OTHER

In crossover design, this test meal with high glycemic index and kefir was served as a breakfast to compare the LGI-Milk Breakfast and the LGI-Kefir Breakfast.

Interventions

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LGI-Milk Breakfast

This test meal with low glycemic index and milk were served as a breakfast after 12-hours fasting and participants were asked to consume the meal in full, within 15 min.

Intervention Type OTHER

LGI-Kefir Breakfast

In crossover design, this test meal with low glycemic index and kefir was served as a breakfast to compare the LGI-Milk Breakfast.

Intervention Type OTHER

HGI-Kefir Breakfast

In crossover design, this test meal with high glycemic index and kefir was served as a breakfast to compare the LGI-Milk Breakfast and the LGI-Kefir Breakfast.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy
* Normal-weight (BMI 18.5-25 kg/m2)
* Female
* 21-24 years

Exclusion Criteria

* During the last three months, change more than 5 kg in body weight or following an energy-restricted diet
* Being a vegan
* Having any chronic diseases such as diabetes, hypertension, etc.
* Physician-diagnosed medications or conditions that influence metabolism
* Smoking
* Practicing endurance sports
* Having difficulties with swallowing/eating
* Lack of appetite
* Hypersensitivity for the foods understudy
* Pregnant or lactating
Minimum Eligible Age

21 Years

Maximum Eligible Age

24 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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TC Erciyes University

OTHER

Sponsor Role lead

Responsible Party

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Zeynep Caferoglu, PhD

Assistant Professor Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Erciyes University Faculty of Health Sciences

Kayseri, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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not defined

Identifier Type: -

Identifier Source: org_study_id