Intranasal Midazolam for Pediatric Pre-procedural Sedation and Pre-procedural Anti-anxiety Using sipNose Device - a Randomized Controlled Study

NCT ID: NCT03635398

Last Updated: 2018-08-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-08-31

Study Completion Date

2020-07-31

Brief Summary

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A Three-arm, Randomized Controlled Trial for Pediatric Pre-procedural Sedation and Pre-procedural Anti-anxiety: Intranasal Midazolam by SipNose versus MAD Versus oral administration

Detailed Description

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Conditions

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Procedural Sedation Intra-nasal Delevery Device

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Intranasal Midazolam by SipNose device

Group Type EXPERIMENTAL

Sipnose device

Intervention Type DEVICE

SipNose's intranasal drug delivery platform uses an innovative mechanism that is suposed to improves efficacy, patient compliance and safety

Intranasal Midazolam by MAD (Mucosal Atomization Device)

Group Type ACTIVE_COMPARATOR

MAD (Mucosal Atomization Device)

Intervention Type DEVICE

MAD (Mucosal Atomization Device)

oral administration of midazolam

Group Type ACTIVE_COMPARATOR

midazolam

Intervention Type DRUG

oral administration of midazolam

Interventions

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Sipnose device

SipNose's intranasal drug delivery platform uses an innovative mechanism that is suposed to improves efficacy, patient compliance and safety

Intervention Type DEVICE

MAD (Mucosal Atomization Device)

MAD (Mucosal Atomization Device)

Intervention Type DEVICE

midazolam

oral administration of midazolam

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* every child \>1y who is intended for medical procedure in the emrgency room(suce as: IV insertion, blood sample collection, urinary catether insertion, laceration repair

Exclusion Criteria

* ASA\>2
* Active respiratory infection
* systemic illness
* Allergy to Midazolam
Minimum Eligible Age

1 Year

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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SipNose

UNKNOWN

Sponsor Role collaborator

Rabin Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Schneider Children's Medical Center of Israel

Petah Tikva, , Israel

Site Status

Countries

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Israel

Other Identifiers

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RMC-17-0435

Identifier Type: -

Identifier Source: org_study_id

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