Effects of Deepure(Pu-erh Tea Extract) on Glycemic Control

NCT ID: NCT03613688

Last Updated: 2018-10-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-09-20

Study Completion Date

2019-07-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This is a randomized, controlled, cross-over study on the effects of consumption of Deepure puerh tea extract (PTE) on glucose tolerance and metabolic markers.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The study will involve consuming three different doses: 1 gram, 1.5 grams, and 2 grams, and will be given in warm water, with a bland meal. The effects on glucose and insulin after consumption will be evaluated.The subjects will be randomly assigned to one of four groups with different sequences.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Glucose Metabolism Disorders

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Deepure Group A

Visit 3: Warm water without Deepure; Visit 4: Warm water with 1 g Deepure; Visit 5: Warm water with 1.5 g Deepure; Visit 6: Warm water with 2 g Deepure.

Group Type EXPERIMENTAL

Deepure

Intervention Type DIETARY_SUPPLEMENT

Pu'erh Tea extract

Deepure Group B

Visit 3: Warm water with 1 g Deepure; Visit 4: Warm water with 1.5 g Deepure; Visit 5: Warm water with 2 g Deepure; Visit 6: Warm water without Deepure.

Group Type EXPERIMENTAL

Deepure

Intervention Type DIETARY_SUPPLEMENT

Pu'erh Tea extract

Deepure Group C

Visit 3: Warm water with 1.5 g Deepure; Visit 4: Warm water with 2 g Deepure; Visit 5: Warm water without Deepure; Visit 6: Warm water with 1 g Deepure.

Group Type EXPERIMENTAL

Deepure

Intervention Type DIETARY_SUPPLEMENT

Pu'erh Tea extract

Deepure Group D

Visit 3: Warm water with 2 g Deepure; Visit 4: Warm water without Deepure; Visit 5: Warm water with 1 g Deepure; Visit 6: Warm water with 1.5 g Deepure.

Group Type EXPERIMENTAL

Deepure

Intervention Type DIETARY_SUPPLEMENT

Pu'erh Tea extract

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Deepure

Pu'erh Tea extract

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Men and women;
* Aged 18-70 years;
* BMI between 20-30;
* Fasting blood glucose at screening between 71-125 mg/dL. both inclusive.

Exclusion Criteria

* Taking dietary supplements judged to interfere with the effects of Deepure on glucose metabolism (for example: cinnamon extract; chromium picolinate; mulberry extract; bitter melon extract, green tea extracts, black tea extracts, pu-erh tea);
* Participation in other clinical trials, involving an investigational product or lifestyle change, during the last month;
* Participation in another research study during this trial, involving an investigational product or lifestyle change; Taking prescription medication known to affect glucose metabolism;
* Taking over-the-counter medication known to affect glucose metabolism;
* Drinking 3 or more cups of tea daily;
* Unwilling to abstain from drinking tea for 24 hours before clinic visits; (if a person drinks tea within 24 hours of a clinic visit, the person's visit will be re-scheduled);
* Consuming 2 or more drinks of alcohol per day;
* Unwilling to abstain from drinking alcohol for 10 hours before clinic visits;
* Diagnosed with diabetes Type I; Taking medication for diabetes Type II;
* Diagnosed with the thyroid disorder Hashimoto's disease;
* Past major surgery to your stomach or intestines (minor surgery not a problem such as hernia repair, appendix removal, gallbladder removal);
* Currently taking cholesterol-lowering medication (for example: statins);
* Currently taking coumadin;
* Major trauma within the past 6 months;
* Major surgery within the past 6 months;
* Severe chronic infectious disease (such as HIV, chronic hepatitis);
* Active depression;
* Self-reported eating disorders;
* History of drug abuse during past two years;
* Currently going through intense stressful events or life changes;
* Women of child-bearing potential: Pregnant, breast-feeding, or trying to become pregnant;
* Women of child-bearing potential: Not using effective contraception;
* Food allergies or sensitivities to tea.
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Natural Immune Systems Inc

OTHER

Sponsor Role collaborator

Tasly Pharmaceuticals, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

NIS labs

Klamath Falls, Oregon, United States

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Gitte Jensen

Role: CONTACT

Phone: (541) 884-0112

Email: [email protected]

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Gitte Jensen

Role: primary

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

079-007

Identifier Type: -

Identifier Source: org_study_id