Integrated Hypertension and HIV Care Cascades in Uganda

NCT ID: NCT03605043

Last Updated: 2018-07-30

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 1649 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2014-01-01
• Study Completion Date: 2018-05-30

Brief Summary

In this retrospective cohort study, we mapped the care cascades for both Hypertension and HIV within a HIV program in Uganda with the goal of identifying opportunities for developing contextually appropriate integrated care models, .

Detailed Description

Persons living with HIV (PLHIV) and receiving anti-retroviral therapy (ART) are at increased risk of cardiovascular disease (CVD) due to direct effects of ART and HIV infection itself, compounded by traditional CVD risk factors such as increased life expectancy and Westernized diet. Additionally, in sub-Saharan Africa, as is the case globally, hypertension (HTN) is a major risk factor for CVD. The prevalence of HTN in the setting of HIV reported in the literature is variable but may be higher than in the HIV-negative population.

World Health Organization (WHO) and Ugandan national HIV guidelines have recommended the integration of hypertension care into HIV programs since 2014 and 2016, but there has been limited uptake of this recommendation in practice. There have been successful efforts to integrate tuberculosis, malaria, nutrition, maternal-child health, and family planning into HIV programmes in Uganda. In this study, with the goal of identifying opportunities for developing contextually appropriate integrated care models, we mapped the care cascades for both HTN and HIV within a HIV program in Uganda.

Conditions

Hypertension; HIV

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Study Groups

Overall cohort

All Persons Living with HIV who enlisted in any one of three high-volume HIV clinics in Tororo District of Eastern Uganda between 2014 and 2017.

Blood pressure management in the HIV program

Intervention Type: OTHER

Integrated care for hypertension and HIV in the HIV program

Interventions

Blood pressure management in the HIV program

Integrated care for hypertension and HIV in the HIV program

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• 18 years of age and above, Having started Antiretroviral therapy between January 2014 and January 2017.

Exclusion Criteria

• PLHIV receiving treatment from clinics other than the 3 selected sites.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Makerere University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Makerere University College of Health Sciences

Kampala, Central Region, Uganda

Countries

Uganda

Other Identifiers

ss 4583

Identifier Type: -

Identifier Source: org_study_id