Investigation on the Efficacy of WO 2085 Moisturising Cream for Breast Cancer Patients Suffering From Vulvovaginal Dryness

NCT ID: NCT03593122

Last Updated: 2018-07-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

128 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-01-04

Study Completion Date

2010-07-31

Brief Summary

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The aim of the study is to gain further experience with regard to the performance of the medical device WO2085 Moisturising Cream for breast cancer patients undergoing chemotherapy or treatment with anti-oestrogens / aromatase inhibitors

Detailed Description

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The goal of this application study was to answer the question as to whether the application of WO2085 Moisturising Cream for breast cancer patients undergoing chemotherapy or treatment with anti-oestrogens / aromatase inhibitors can result in an improvement in the subjective symptoms and objective diagnoses of vulvovaginal dryness while also ensuring good tolerability.

Conditions

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Vulvovaginal Atrophy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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WO 2085 Moisturising Cream

WO2085 is a hormone-free Moisturizing Cream and is used to treat "vulvovaginal dryness" symptoms.

Group Type EXPERIMENTAL

WO2085 Moisturising Cream

Intervention Type DEVICE

Week 1: 2.5 g of the investigational product WO2085 Moisturising Cream will be applied intravaginally, once daily in the evening. In addition 0.5 g (1 fingertip unit) may be applied to the outer genital area as needed (also several times per day).

Week 2-4: The frequency may be reduced by the patient as needed. In addition 0.5 g (1 fingertip unit) may be applied to the outer genital area as needed (also several times per day).

Interventions

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WO2085 Moisturising Cream

Week 1: 2.5 g of the investigational product WO2085 Moisturising Cream will be applied intravaginally, once daily in the evening. In addition 0.5 g (1 fingertip unit) may be applied to the outer genital area as needed (also several times per day).

Week 2-4: The frequency may be reduced by the patient as needed. In addition 0.5 g (1 fingertip unit) may be applied to the outer genital area as needed (also several times per day).

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Women with breast cancer undergoing chemotherapy OR therapy with aromatase inhibitors or anti-oestrogens (either at present or up to 3 months after ending treatment) AND with symptoms of vulvovaginal dryness since the start of tumour treatment
* Written declaration of consent for the voluntary participation in the study is present

Exclusion Criteria

* Women who suffered symptoms of vulvovaginal dryness prior to the start of tumour treatment
* Patients undergoing radiation therapy
* Patients with other tumours
* A current vaginal infection
* Medical conditions related to the vulva or vagina
* Current additional therapy of vulvovaginal dryness or vulvovaginal atrophy
* Women who are not able to participate properly in this study
* Current alcohol and/or drug abuse
* Pregnant or lactating women
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Dr. Dimitrios Chatsiproios

UNKNOWN

Sponsor Role collaborator

Dr. med. Klaus König

UNKNOWN

Sponsor Role collaborator

SAM®, Statistische Analysen und Monitoring GmbH

UNKNOWN

Sponsor Role collaborator

Dr. August Wolff GmbH & Co. KG Arzneimittel

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Prof. Christoph Abels, MD, PhD

Role: STUDY_DIRECTOR

Dr. August Wolff GmbH & Co. KG Arzneimittel

Locations

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Axel Gerick

Aachen, , Germany

Site Status

Sibylle Kaßpohl

Alzenau in Unterfranken, , Germany

Site Status

Jörg Schilling

Berlin, , Germany

Site Status

Axel Widing

Berlin, , Germany

Site Status

Alexandra Coumbos

Berlin, , Germany

Site Status

Amin Mortazawi

Darmstadt, , Germany

Site Status

Kathrin von Ardenne

Dresden, , Germany

Site Status

Joachim Larbig

Fulda, , Germany

Site Status

Nidal Gazawi

Leipzig, , Germany

Site Status

Elke Wierick

Lohsa, , Germany

Site Status

Dagmar Guth

Plauen, , Germany

Site Status

Wolfgang Clemens

Stolberg, , Germany

Site Status

Carsten Hielscher

Stralsund, , Germany

Site Status

Christopher Wolf

Ulm, , Germany

Site Status

Heidi Massinger-Biebl

Waldkirchen, , Germany

Site Status

Klaus Doubek

Wiesbaden, , Germany

Site Status

Anja Obermeyer

Würselen, , Germany

Site Status

Countries

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Germany

Other Identifiers

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VFAU-13/2009

Identifier Type: -

Identifier Source: org_study_id

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