Improve Acute Reperfusion Treatment Quality for Stroke in China, IMPROVE: Stroke Care in China
NCT ID: NCT03578107
Last Updated: 2021-11-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
15895 participants
INTERVENTIONAL
2018-07-01
2020-10-31
Brief Summary
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Detailed Description
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Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
HEALTH_SERVICES_RESEARCH
SINGLE
Study Groups
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Improvement intervention1
receive the following improvement intervention for 18 months：
improvement of quality of stroke care
1. hospital tool kits for quality improvement of reperfusion therapy ;
2. organizational stakeholder and opinion leader meetings;
3. data monitoring and feedback reports；
4. webinar for hospital teams
Improvement intervention2
receive the following improvement intervention for 12 months：
improvement of quality of stroke care
1. hospital tool kits for quality improvement of reperfusion therapy ;
2. organizational stakeholder and opinion leader meetings;
3. data monitoring and feedback reports；
4. webinar for hospital teams
Improvement intervention3
receive the following improvement intervention for 6 months：
improvement of quality of stroke care
1. hospital tool kits for quality improvement of reperfusion therapy ;
2. organizational stakeholder and opinion leader meetings;
3. data monitoring and feedback reports；
4. webinar for hospital teams
Interventions
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improvement of quality of stroke care
1. hospital tool kits for quality improvement of reperfusion therapy ;
2. organizational stakeholder and opinion leader meetings;
3. data monitoring and feedback reports；
4. webinar for hospital teams
Eligibility Criteria
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Inclusion Criteria
1. Voluntary.
2. Hospitals from CSCA.
3. Secondary or tertiary public hospitals with an emergency department and neurologic wards that receive patients with AIS.
4. Have a 24\*7 on-call stroke team.
5. Have the capacity of IV rt-PA thrombolytic therapy or/and endovascular treatment.
6. Implement at least 10 patients' rt-PA or/and endovascular treatment during the last year.
7. Admit at least 5 patients of acute ischemic stroke within 24 hours after onset each month.
8. Have full desire to improve the procedure of treatment of acute ischemic stroke.
9. Have good cooperation among Neurology department, Emergency department, Interventional department, Neurosurgery department, Laboratory and Radiology department.
Patients： Patients who are ≥18 years old were eligible for inclusion if they presented with acute ischemic stroke diagnosed by CT and/or MRI and arrived at hospital within 6 hours after symptom onset.
Exclusion Criteria
1. Hospitals that can not comply with the protocol and finish the research.
2. Grade-one hospitals and non cerebral vascular disease specialized hospitals.
3. Hospitals involved in other stroke care quality improvement projects or relevant clinical trials.
Patients：
1）Patients refuse to participate in this study
18 Years
ALL
No
Sponsors
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American Heart Association
OTHER
Beijing Tiantan Hospital
OTHER
Responsible Party
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Yongjun Wang
Executive Vice-President
Principal Investigators
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Yongjun Wang, MD
Role: PRINCIPAL_INVESTIGATOR
Beijing Tiantan Hospital
Locations
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Beijing Tiantan Hospital, Capital Medical University
Beijing, Beijing Municipality, China
Countries
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References
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Wang CJ, Gu HQ, Zong LX, Zhang XM, Zhou Q, Jiang Y, Li H, Meng X, Yang X, Wang M, Huo XC, Wangqin RQ, Bei YZ, Qi XH, Liu XY, Hu SQ, Wang ZM, Zhao XQ, Wang YL, Liu LP, Ma XD, Morgan L, Xian Y, Schwamm LH, Wang YJ, Li ZX; IMPROVE Stroke Care in China investigators. Effectiveness of a Quality Improvement Intervention on Reperfusion Treatment for Patients With Acute Ischemic Stroke: A Stepped-Wedge Cluster Randomized Clinical Trial. JAMA Netw Open. 2023 Jun 1;6(6):e2316465. doi: 10.1001/jamanetworkopen.2023.16465.
Li Z, Wang C, Zhang X, Zong L, Zhou H, Gu H, Jiang Y, Pan Y, Meng X, Zhou Q, Zhao H, Yang X, Wang M, Xiong Y, Zhao X, Wang Y, Liu L, Ma X, Morgan L, Xian Y, Schwamm LH, Wang Y. Rationale and design of a stepped wedge cluster randomised trial to improve acute reperfusion treatment quality for stroke: IMPROVE stroke care in China. Stroke Vasc Neurol. 2022 Oct;7(5):451-456. doi: 10.1136/svn-2021-001461. Epub 2022 Mar 30.
Other Identifiers
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KY 2018-044-01
Identifier Type: -
Identifier Source: org_study_id