Gait Retraining to Reduce Joint Loading, Inflammation, and PTOA Risk

NCT ID: NCT03551678

Last Updated: 2020-10-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-06-21

Study Completion Date

2022-12-31

Brief Summary

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The purpose of this study is to determine changes to knee joint loading, biological markers, and cartilage structure following a novel active feedback gait retraining program in anterior cruciate ligament reconstructed patients.

Detailed Description

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Conditions

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Anterior Cruciate Ligament Reconstruction

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Gait retraining

Eight weeks of active-feedback gait retraining. The gait retraining device measures pressure/force under the lateral side of the foot and activates vibration if loading crosses a set threshold. The location of the vibration is customized for each subject to achieve maximal sensitivity.

Group Type EXPERIMENTAL

Active feedback gait retraining

Intervention Type DEVICE

The device measures pressure/force under the lateral side of the foot and activates vibration if loading crosses a set threshold. The location of the vibration is customized for each subject to achieve maximal sensitivity.

Interventions

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Active feedback gait retraining

The device measures pressure/force under the lateral side of the foot and activates vibration if loading crosses a set threshold. The location of the vibration is customized for each subject to achieve maximal sensitivity.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* age 18-40 years
* history of primary ACLR with or without meniscal repair
* full weight-bearing status
* neutral to varus knee alignment
* plans to remain in the area for at least 8 months.

Exclusion Criteria

* Kellgren-Lawrence (KL) radiographic grade \> 2
* additional injury or surgery to the involved knee
* BMI \>30 kg/m2
* use of walking, orthopedic, or prosthetic assistive device
* pregnancy
* inability to have MRI
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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United States Department of Defense

FED

Sponsor Role collaborator

VA Palo Alto Health Care System

FED

Sponsor Role lead

Responsible Party

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Constance Chu, MD

Study Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Constance Chu, MD

Role: PRINCIPAL_INVESTIGATOR

VAPAHCS and Stanford University

Locations

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VA Palo Alto

Palo Alto, California, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Jennifer Hledik, PhD

Role: CONTACT

650-493-5000 ext. 62388

Jessica Asay, MS

Role: CONTACT

Facility Contacts

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Constance R Chu, MD

Role: primary

650-721-7618

Other Identifiers

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CDMRP-PR171647

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

46025

Identifier Type: -

Identifier Source: org_study_id