Laboratory Smoking of Marijuana "Blunts"

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

8 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-04-10

Study Completion Date

2019-09-30

Brief Summary

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This is a double-blind within-subjects clinical laboratory study comparing the product appeal and abuse liability-related subjective effects of different flavored cigar wrappers for marijuana blunts.

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Detailed Description

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Conditions

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Cannabis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Flavor 1

Grape flavored tobacco cigar wrapper

Group Type EXPERIMENTAL

Marijuana

Intervention Type DRUG

Marijuana smoked via blunts with different cigar wrappers

Flavor 2

Chocolate flavored tobacco cigar wrapper

Group Type EXPERIMENTAL

Marijuana

Intervention Type DRUG

Marijuana smoked via blunts with different cigar wrappers

Flavor 3

Tobacco flavored tobacco cigar wrapper

Group Type EXPERIMENTAL

Marijuana

Intervention Type DRUG

Marijuana smoked via blunts with different cigar wrappers

Interventions

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Marijuana

Marijuana smoked via blunts with different cigar wrappers

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Currently living in Baltimore City or Baltimore County, MD;
* Able to read, understand, and sign informed consent;
* 18-55 years old;
* Currently smokes marijuana blunts;
* Designation of Medically Healthy for Research by the Study Physician; and
* Willing to abstain from illicit drug use other than marijuana for the duration of the study.

Exclusion Criteria

* BAC \> 0.020% as measured by alcohol breathalyzer;
* Meets DSM-5 criteria for severe current or lifetime Cannabis Use Disorder;
* Meets DSM-5 criteria for any current Axis I disorder, other than current mild or moderate Cannabis Use Disorder;
* Self-reported current desire to stop marijuana use;
* Self-reported current asthma, chronic obstructive pulmonary disease, hypertension, cardiovascular disease or any other medical illness that precludes participation;
* Has difficulties with blood draws or poor venous access;
* History of blood donation in the past 30 days or receiving blood products within the past 2 months prior to any experimental visit;
* Among females, current pregnancy or lactation or attempting to get pregnant, or at risk of becoming pregnant;
* Acute illness which will require participant to be rescheduled

Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes