Trial Outcomes & Findings for Taekwondo Training and Postmenopausal Women With Stage-2 Hypertension (NCT NCT03544307)
NCT ID: NCT03544307
Last Updated: 2020-11-10
Results Overview
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
20 participants
Primary outcome timeframe
12-weeks
Results posted on
2020-11-10
Participant Flow
Participant milestones
| Measure |
Taekwondo Training
Taekwondo training was performed 60 minutes/day, 3 days/week for 12-weeks. Exercise intensity was set at 30-40% of heart rate reserve (HRR) and gradually increased to 50-60% over 12 weeks.
Taekwondo training: Exercise group
|
Control
Sedentary control asked not to exercise
|
|---|---|---|
|
Overall Study
STARTED
|
10
|
10
|
|
Overall Study
COMPLETED
|
10
|
10
|
|
Overall Study
NOT COMPLETED
|
0
|
0
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Taekwondo Training and Postmenopausal Women With Stage-2 Hypertension
Baseline characteristics by cohort
| Measure |
Taekwondo Training
n=10 Participants
Taekwondo training was performed 60 minutes/day, 3 days/week for 12-weeks. Exercise intensity was set at 30-40% of heart rate reserve (HRR) and gradually increased to 50-60% over 12 weeks.
Taekwondo training: Exercise group
|
Control
n=10 Participants
Sedentary control asked not to exercise
|
Total
n=20 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Categorical
<=18 years
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Age, Categorical
Between 18 and 65 years
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Age, Categorical
>=65 years
|
10 Participants
n=5 Participants
|
10 Participants
n=7 Participants
|
20 Participants
n=5 Participants
|
|
Age, Continuous
|
70 years
STANDARD_DEVIATION 4 • n=5 Participants
|
70 years
STANDARD_DEVIATION 4 • n=7 Participants
|
70 years
STANDARD_DEVIATION 4.7 • n=5 Participants
|
|
Sex: Female, Male
Female
|
10 Participants
n=5 Participants
|
10 Participants
n=7 Participants
|
20 Participants
n=5 Participants
|
|
Sex: Female, Male
Male
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Asian
|
10 Participants
n=5 Participants
|
10 Participants
n=7 Participants
|
20 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Black or African American
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
White
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
More than one race
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Region of Enrollment
South Korea
|
10 participants
n=5 Participants
|
10 participants
n=7 Participants
|
20 participants
n=5 Participants
|
|
Blood epinephrine levels
|
43.6 pg/mL
STANDARD_DEVIATION 6.6 • n=5 Participants
|
43.4 pg/mL
STANDARD_DEVIATION 5.1 • n=7 Participants
|
43.5 pg/mL
STANDARD_DEVIATION 5.9 • n=5 Participants
|
|
Blood norepinephrine levels
|
268.6 pg/mL
STANDARD_DEVIATION 41.3 • n=5 Participants
|
243.4 pg/mL
STANDARD_DEVIATION 5.1 • n=7 Participants
|
256 pg/mL
STANDARD_DEVIATION 23.2 • n=5 Participants
|
|
Arterial stiffness
|
8.41 m/s
STANDARD_DEVIATION 1.0 • n=5 Participants
|
8.27 m/s
STANDARD_DEVIATION 0.67 • n=7 Participants
|
8.34 m/s
STANDARD_DEVIATION 0.84 • n=5 Participants
|
|
Systolic Blood Pressure
|
144 mmHg
STANDARD_DEVIATION 2 • n=5 Participants
|
143 mmHg
STANDARD_DEVIATION 2 • n=7 Participants
|
144 mmHg
STANDARD_DEVIATION 2 • n=5 Participants
|
|
Diastolic Blood Pressure
|
98 mmHg
STANDARD_DEVIATION 2 • n=5 Participants
|
99 mmHg
STANDARD_DEVIATION 2 • n=7 Participants
|
99 mmHg
STANDARD_DEVIATION 2 • n=5 Participants
|
|
Hand grip strength
|
24 kg
STANDARD_DEVIATION 4 • n=5 Participants
|
25 kg
STANDARD_DEVIATION 4 • n=7 Participants
|
25 kg
STANDARD_DEVIATION 4 • n=5 Participants
|
|
Leg strength
|
39 kg
STANDARD_DEVIATION 6 • n=5 Participants
|
38 kg
STANDARD_DEVIATION 7 • n=7 Participants
|
39 kg
STANDARD_DEVIATION 7 • n=5 Participants
|
PRIMARY outcome
Timeframe: 12-weeksOutcome measures
| Measure |
Control
n=10 Participants
Sedentary control asked not to exercise
|
Taekwondo Training
n=10 Participants
Taekwondo training was performed 60 minutes/day, 3 days/week for 12-weeks. Exercise intensity was set at 30-40% of heart rate reserve (HRR) and gradually increased to 50-60% over 12 weeks.
Taekwondo training: Exercise group
|
|---|---|---|
|
Blood Epinephrine Levels
|
46.2 pg/mL
Standard Deviation 4.7
|
39.3 pg/mL
Standard Deviation 7.1
|
PRIMARY outcome
Timeframe: 12-weeksOutcome measures
| Measure |
Control
n=10 Participants
Sedentary control asked not to exercise
|
Taekwondo Training
n=10 Participants
Taekwondo training was performed 60 minutes/day, 3 days/week for 12-weeks. Exercise intensity was set at 30-40% of heart rate reserve (HRR) and gradually increased to 50-60% over 12 weeks.
Taekwondo training: Exercise group
|
|---|---|---|
|
Blood Norepinephrine Levels
|
330 pg/mL
Standard Deviation 38.2
|
232.2 pg/mL
Standard Deviation 33.7
|
SECONDARY outcome
Timeframe: 12-weeksPulse Wave Velocity
Outcome measures
| Measure |
Control
n=10 Participants
Sedentary control asked not to exercise
|
Taekwondo Training
n=10 Participants
Taekwondo training was performed 60 minutes/day, 3 days/week for 12-weeks. Exercise intensity was set at 30-40% of heart rate reserve (HRR) and gradually increased to 50-60% over 12 weeks.
Taekwondo training: Exercise group
|
|---|---|---|
|
Arterial Stiffness
|
8.48 m/s
Standard Deviation 1.0
|
7.67 m/s
Standard Deviation 1.0
|
SECONDARY outcome
Timeframe: 12-weeksOutcome measures
| Measure |
Control
n=10 Participants
Sedentary control asked not to exercise
|
Taekwondo Training
n=10 Participants
Taekwondo training was performed 60 minutes/day, 3 days/week for 12-weeks. Exercise intensity was set at 30-40% of heart rate reserve (HRR) and gradually increased to 50-60% over 12 weeks.
Taekwondo training: Exercise group
|
|---|---|---|
|
Systolic Blood Pressure
|
142 mmHg
Standard Deviation 2
|
130 mmHg
Standard Deviation 2
|
SECONDARY outcome
Timeframe: 12-weeksOutcome measures
| Measure |
Control
n=10 Participants
Sedentary control asked not to exercise
|
Taekwondo Training
n=10 Participants
Taekwondo training was performed 60 minutes/day, 3 days/week for 12-weeks. Exercise intensity was set at 30-40% of heart rate reserve (HRR) and gradually increased to 50-60% over 12 weeks.
Taekwondo training: Exercise group
|
|---|---|---|
|
Hand Grip Strength
|
24 kilograms (kg)
Standard Deviation 4
|
27 kilograms (kg)
Standard Deviation 3
|
SECONDARY outcome
Timeframe: 12-weeksOutcome measures
| Measure |
Control
n=10 Participants
Sedentary control asked not to exercise
|
Taekwondo Training
n=10 Participants
Taekwondo training was performed 60 minutes/day, 3 days/week for 12-weeks. Exercise intensity was set at 30-40% of heart rate reserve (HRR) and gradually increased to 50-60% over 12 weeks.
Taekwondo training: Exercise group
|
|---|---|---|
|
Diastolic Blood Pressure
|
97 mmHg
Standard Deviation 2
|
87 mmHg
Standard Deviation 2
|
SECONDARY outcome
Timeframe: 12-weeksOutcome measures
| Measure |
Control
n=10 Participants
Sedentary control asked not to exercise
|
Taekwondo Training
n=10 Participants
Taekwondo training was performed 60 minutes/day, 3 days/week for 12-weeks. Exercise intensity was set at 30-40% of heart rate reserve (HRR) and gradually increased to 50-60% over 12 weeks.
Taekwondo training: Exercise group
|
|---|---|---|
|
Leg Strength
|
38 kilograms (kg)
Standard Deviation 8
|
41 kilograms (kg)
Standard Deviation 7
|
Adverse Events
Taekwondo Training
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Control
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Dr. Song-Young Park
The University of Nebraska at Omaha
Phone: 402-554-3774
Email: [email protected]
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place